Max T. Huang, Ph.D.

Affiliations: 
2010 Oral Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Neuroinflammation
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"Max Huang"
Mean distance: 19.07 (cluster 11)
 

Parents

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Jenny P-Y Ting grad student 2010 UNC Chapel Hill
 (Critical roles of inflammasome components NLRs, PYCARD, and caspase-1 in host - pathogen interactions.)
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Publications

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Taxman DJ, Swanson KV, Broglie PM, et al. (2012) Porphyromonas gingivalis mediates inflammasome repression in polymicrobial cultures through a novel mechanism involving reduced endocytosis. The Journal of Biological Chemistry. 287: 32791-9
Kovarova M, Hesker PR, Jania L, et al. (2012) NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 2006-16
Taxman DJ, Holley-Guthrie EA, Huang MT, et al. (2011) The NLR adaptor ASC/PYCARD regulates DUSP10, mitogen-activated protein kinase (MAPK), and chemokine induction independent of the inflammasome. The Journal of Biological Chemistry. 286: 19605-16
Wen H, Gris D, Lei Y, et al. (2011) Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nature Immunology. 12: 408-15
Davis BK, Roberts RA, Huang MT, et al. (2011) Cutting edge: NLRC5-dependent activation of the inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 186: 1333-7
Huang MT, Mortensen BL, Taxman DJ, et al. (2010) Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis. Journal of Immunology (Baltimore, Md. : 1950). 185: 5476-85
Taxman DJ, Huang MT, Ting JP. (2010) Inflammasome inhibition as a pathogenic stealth mechanism. Cell Host & Microbe. 8: 7-11
Gris D, Ye Z, Iocca HA, et al. (2010) NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 974-81
Moore CB, Guthrie EH, Huang MT, et al. (2010) Short hairpin RNA (shRNA): design, delivery, and assessment of gene knockdown. Methods in Molecular Biology (Clifton, N.J.). 629: 141-58
Willingham SB, Allen IC, Bergstralh DT, et al. (2009) NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. Journal of Immunology (Baltimore, Md. : 1950). 183: 2008-15
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