Charles W. Bugg, Ph.D.

Affiliations: 
2011 Biochemistry and Molecular Biophysics California Institute of Technology, Pasadena, CA 
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"Charles Bugg"
Mean distance: 14.39 (cluster 11)
 
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Paul H. Patterson grad student 2011 Caltech
 (Domain organization of mutant huntingtin fibrils.)
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Publications

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Bugg CW, Isas JM, Fischer T, et al. (2012) Structural features and domain organization of huntingtin fibrils. The Journal of Biological Chemistry. 287: 31739-46
Southwell AL, Bugg CW, Kaltenbach LS, et al. (2011) Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1. Plos One. 6: e16676
Southwell AL, Khoshnan A, Dunn DE, et al. (2008) Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9013-20
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