Thomas J. Klein, Ph.D.

Affiliations: 
2006 Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Developmental genetics/drosophila retina/planar polarity
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"Thomas Klein"
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Marek Mlodzik grad student 2006 Mount Sinai School of Medicine
 (Molecular mechanisms regulating Frizzled receptor signal specificity.)
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Publications

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Du A, McCracken KW, Walp ER, et al. (2012) Arx is required for normal enteroendocrine cell development in mice and humans. Developmental Biology. 365: 175-88
Abdeljabbar DM, Klein TJ, Link AJ. (2011) An engineered methionyl-tRNA synthetase enables azidonorleucine incorporation in methionine prototrophic bacteria. Chembiochem : a European Journal of Chemical Biology. 12: 1699-702
Abdeljabbar DM, Klein TJ, Zhang S, et al. (2009) A single genomic copy of an engineered methionyl-tRNA synthetase enables robust incorporation of azidonorleucine into recombinant proteins in E. coli. Journal of the American Chemical Society. 131: 17078-9
Simons M, Gault WJ, Gotthardt D, et al. (2009) Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization. Nature Cell Biology. 11: 286-94
Klein TJ, Jenny A, Djiane A, et al. (2006) CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila. Current Biology : Cb. 16: 1337-43
Klein TJ, Mlodzik M. (2005) Planar cell polarization: an emerging model points in the right direction. Annual Review of Cell and Developmental Biology. 21: 155-76
Das G, Jenny A, Klein TJ, et al. (2004) Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes. Development (Cambridge, England). 131: 4467-76
Wu J, Klein TJ, Mlodzik M. (2004) Subcellular localization of frizzled receptors, mediated by their cytoplasmic tails, regulates signaling pathway specificity. Plos Biology. 2: E158
Klein TJ, Mlodzik M. (2004) A conserved signaling cassette regulates hair patterning from Drosophila to man. Proceedings of the National Academy of Sciences of the United States of America. 101: 9173-4
Mahrholz T, Klein J, Klein T. (2004) New Poly(Sodium Carboxylate)s Based on Saccharides. II. Cobuilder Performance of Ionic Allyl Glycoside Polymers as Substitutes of Standard Polycarboxylates Journal of Macromolecular Science - Pure and Applied Chemistry. 41: 165-179
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