Luis R. Gardell, Ph.D.

Affiliations: 
2002 University of Arizona, Tucson, AZ 
Area:
pain, opioids, pharmacology
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"Luis Gardell"
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Parents

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Frank Porreca grad student 2002 University of Arizona
 (Dynorphin promotes opioid-induced abnormal pain and antinociceptive tolerance.)
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Publications

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Lameh J, Bertozzi F, Kelly N, et al. (2010) Neuropeptide FF receptors have opposing modulatory effects on nociception. The Journal of Pharmacology and Experimental Therapeutics. 334: 244-54
Schlienger N, Lund BW, Pawlas J, et al. (2009) Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators. Journal of Medicinal Chemistry. 52: 7186-91
Gaubert G, Bertozzi F, Kelly NM, et al. (2009) Discovery of selective nonpeptidergic neuropeptide FF2 receptor agonists. Journal of Medicinal Chemistry. 52: 6511-4
Pettersson H, Bülow A, Ek F, et al. (2009) Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists. Journal of Medicinal Chemistry. 52: 1975-82
Fioravanti B, De Felice M, Stucky CL, et al. (2008) Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11593-602
Gardell LR, Ma JN, Seitzberg JG, et al. (2008) Identification and characterization of novel small-molecule protease-activated receptor 2 agonists. The Journal of Pharmacology and Experimental Therapeutics. 327: 799-808
Gardell LR, Hyldtoft L, Del Tredici AL, et al. (2008) Differential modulation of inflammatory pain by a selective estrogen receptor beta agonist. European Journal of Pharmacology. 592: 158-9
Piu F, Cheevers C, Hyldtoft L, et al. (2008) Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist. European Journal of Pharmacology. 590: 423-9
Piu F, Gardell LR, Son T, et al. (2008) Pharmacological characterization of AC-262536, a novel selective androgen receptor modulator. The Journal of Steroid Biochemistry and Molecular Biology. 109: 129-37
Acevedo S, Gardell L, Bradley SR, et al. (2008) Selective androgen receptor modulators antagonize apolipoprotein E4-induced cognitive impairments Letters in Drug Design and Discovery. 5: 271-276
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