Adam S. Crystal, Ph.D.

2005 University of Pennsylvania, Philadelphia, PA, United States 
tau, dementia, neurodegeneration
"Adam Crystal"
Mean distance: 16.53 (cluster 24)


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Virginia Man-Yee Lee grad student 2005 Penn
 (Amyloid beta generation: Towards understanding the role of Pen-2 in the gamma-secretase complex, and, A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114.)
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Hata AN, Niederst MJ, Archibald HL, et al. (2016) Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition. Nature Medicine
Morais VA, Brito C, Pijak DS, et al. (2006) N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53. Biochimica Et Biophysica Acta. 1762: 802-10
Crystal AS, Morais VA, Fortna RR, et al. (2004) Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation. Biochemistry. 43: 3555-63
Fortna RR, Crystal AS, Morais VA, et al. (2004) Membrane topology and nicastrin-enhanced endoproteolysis of APH-1, a component of the gamma-secretase complex. The Journal of Biological Chemistry. 279: 3685-93
Crystal AS, Giasson BI, Crowe A, et al. (2003) A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114. Journal of Neurochemistry. 86: 1359-68
Morais VA, Crystal AS, Pijak DS, et al. (2003) The transmembrane domain region of nicastrin mediates direct interactions with APH-1 and the gamma-secretase complex. The Journal of Biological Chemistry. 278: 43284-91
Crystal AS, Morais VA, Pierson TC, et al. (2003) Membrane topology of gamma-secretase component PEN-2. The Journal of Biological Chemistry. 278: 20117-23
Price RA, Li WD, Bernstein A, et al. (2001) A locus affecting obesity in human chromosome region 10p12 Diabetologia. 44: 363-366
Bertram L, Guénette S, Jones J, et al. (2001) No evidence for genetic association or linkage of the cathepsin D (CTSD) exon 2 polymorphism and Alzheimer disease. Annals of Neurology. 49: 114-6
Bertram L, Blacker D, Crystal A, et al. (2000) Candidate genes showing no evidence for association or linkage with Alzheimer's disease using family-based methodologies. Experimental Gerontology. 35: 1353-61
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