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Deepak M. Sampathu, Ph.D.

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
tau, dementia, neurodegeneration
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"Deepak Sampathu"
Mean distance: 16.53 (cluster 24)
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Virginia Man-Yee Lee grad student 2006 Penn
 (Biochemical studies of pathological inclusions in alpha-synucleinopathies and frontotemporal lobar degeneration with ubiquitin-positive inclusions.)

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Publications

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Mackenzie IR, Neumann M, Baborie A, et al. (2011) A harmonized classification system for FTLD-TDP pathology. Acta Neuropathologica. 122: 111-3
Neumann M, Kwong LK, Sampathu DM, et al. (2007) TDP-43 proteinopathy in frontotemporal lobar degeneration and amyotrophic lateral sclerosis: protein misfolding diseases without amyloidosis. Archives of Neurology. 64: 1388-94
Kwong LK, Neumann M, Sampathu DM, et al. (2007) TDP-43 proteinopathy: the neuropathology underlying major forms of sporadic and familial frontotemporal lobar degeneration and motor neuron disease. Acta Neuropathologica. 114: 63-70
Neumann M, Sampathu DM, Kwong LK, et al. (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science (New York, N.Y.). 314: 130-3
Sampathu DM, Neumann M, Kwong LK, et al. (2006) Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies. The American Journal of Pathology. 169: 1343-52
Meulener MC, Graves CL, Sampathu DM, et al. (2005) DJ-1 is present in a large molecular complex in human brain tissue and interacts with alpha-synuclein. Journal of Neurochemistry. 93: 1524-32
Pawlyk AC, Giasson BI, Sampathu DM, et al. (2003) Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. The Journal of Biological Chemistry. 278: 48120-8
Sampathu DM, Giasson BI, Pawlyk AC, et al. (2003) Ubiquitination of alpha-synuclein is not required for formation of pathological inclusions in alpha-synucleinopathies. The American Journal of Pathology. 163: 91-100
Giasson BI, Sampathu DM, Wilson CA, et al. (2002) The environmental toxin arsenite induces tau hyperphosphorylation. Biochemistry. 41: 15376-87
Galvin JE, Nakamura M, McIntosh TK, et al. (2000) Neurofilament-rich intraneuronal inclusions exacerbate neurodegenerative sequelae of brain trauma in NFH/LacZ transgenic mice. Experimental Neurology. 165: 77-89
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