Soyon Y. Hong, Ph.D.

Affiliations: 
2012 Biology: Medical Sciences, Division of Harvard University, Cambridge, MA, United States 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=1
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"Soyon Hong"
Mean distance: 17.66 (cluster 31)
 
SNBCP

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Dennis J. Selkoe grad student 2012 Harvard
 (Probing the in vivo economy of amyloid beta-protein during the development of Alzheimer's disease-type pathology.)
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Publications

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Schlepckow K, Morenas-Rodríguez E, Hong S, et al. (2023) Stimulation of TREM2 with agonistic antibodies-an emerging therapeutic option for Alzheimer's disease. The Lancet. Neurology. 22: 1048-1060
Rueda-Carrasco J, Sokolova D, Lee SE, et al. (2023) Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models. The Embo Journal. e113246
De Schepper S, Ge JZ, Crowley G, et al. (2023) Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease. Nature Neuroscience
Paolicelli RC, Sierra A, Stevens B, et al. (2022) Microglia states and nomenclature: A field at its crossroads. Neuron. 110: 3458-3483
Hong S, Stevens B. (2017) TREM2: Keeping Microglia Fit during Good Times and Bad. Cell Metabolism. 26: 590-591
Shi Q, Chowdhury S, Ma R, et al. (2017) Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice. Science Translational Medicine. 9
Hong S, Wilton DK, Stevens B, et al. (2017) Structured Illumination Microscopy for the Investigation of Synaptic Structure and Function. Methods in Molecular Biology (Clifton, N.J.). 1538: 155-167
Hong S, Stevens B. (2016) Microglia: Phagocytosing to Clear, Sculpt, and Eliminate. Developmental Cell. 38: 126-8
Hong S, Beja-Glasser VF, Nfonoyim BM, et al. (2016) Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science (New York, N.Y.)
Hong S, Dissing-Olesen L, Stevens B. (2015) New insights on the role of microglia in synaptic pruning in health and disease. Current Opinion in Neurobiology. 36: 128-134
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