Jerri M. Rook, Ph.D.

Affiliations: 
2008 Pharmacology, Toxicology & Therapeutics University of Kansas, Lawrence, KS, United States 
Area:
pain neurobiology
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"Jerri Rook"
Mean distance: 17.56 (cluster 6)
 
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Kenneth E. McCarson grad student 2008 University of Kansas
 (Mechanisms of cutaneous wound healing are mediated via peripheral neuropeptide activity.)
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Publications

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Foster DJ, Wilson JM, Remke DH, et al. (2016) Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release. Neuron
Balu DT, Li Y, Takagi S, et al. (2016) An mGlu5 Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Pancani T, Foster DJ, Moehle MS, et al. (2015) Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice. Proceedings of the National Academy of Sciences of the United States of America. 112: 14078-83
Malosh C, Turlington M, Bridges TM, et al. (2015) Acyl dihydropyrazolo[1,5-a]pyrimidinones as metabotropic glutamate receptor 5 positive allosteric modulators. Bioorganic & Medicinal Chemistry Letters
Garcia-Barrantes PM, Cho HP, Niswender CM, et al. (2015) Development of novel, CNS penetrant positive allosteric modulators for the metabotropic glutamate receptor subtype 1 (mGlu1), based on an N-(3-chloro-4-(1,3-dioxoisoindolin-2-yl)phenyl)-3-methylfuran-2-carboxamide scaffold, that potentiate both wild type and mutant mGlu1 receptors found in schizophrenics. Journal of Medicinal Chemistry
Gould RW, Amato RJ, Bubser M, et al. (2015) Partial mGlu5 Negative Allosteric Modulators Attenuate Cocaine-Mediated Behaviors and Lack Psychotomimetic-Like Effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Ghoshal A, Rook JM, Dickerson JW, et al. (2015) Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Rook JM, Xiang Z, Lv X, et al. (2015) Biased mGlu5-Positive Allosteric Modulators Provide In Vivo Efficacy without Potentiating mGlu5 Modulation of NMDAR Currents. Neuron. 86: 1029-40
Burket JA, Benson AD, Green TL, et al. (2015) Effects of VU0410120, a novel GlyT1 inhibitor, on measures of sociability, cognition and stereotypic behaviors in a mouse model of autism. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 61: 10-7
Walker AG, Wenthur CJ, Xiang Z, et al. (2015) Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction. Proceedings of the National Academy of Sciences of the United States of America. 112: 1196-201
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