Julien Muffat

Affiliations: 
2017- Neurosciences and Mental Health The Hospital for Sick Children / University of Toronto, Toronto, Ontario, Canada 
Area:
stem cells, neurodegeneration, inflammation, pathological aging, microglia, neuro-immune
Google:
"Julien Muffat"
Mean distance: 12.91 (cluster 31)
 
SNBCP
Cross-listing: FlyTree

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Publications

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Li Y, Muffat J, Omer Javed A, et al. (2019) Genome-wide CRISPR screen for Zika virus resistance in human neural cells. Proceedings of the National Academy of Sciences of the United States of America
Omer Javed A, Li Y, Muffat J, et al. (2018) Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Reports. 25: 368-382.e5
Muffat J, Li Y, Omer A, et al. (2018) Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections. Proceedings of the National Academy of Sciences of the United States of America
Liu XS, Wu H, Krzisch M, et al. (2018) Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene. Cell
Li Y, Muffat J, Omer A, et al. (2016) Induction of Expansion and Folding in Human Cerebral Organoids. Cell Stem Cell
Muffat J, Li Y, Jaenisch R. (2016) CNS disease models with human pluripotent stem cells in the CRISPR age. Current Opinion in Cell Biology. 43: 96-103
Muffat J, Li Y, Yuan B, et al. (2016) Efficient derivation of microglia-like cells from human pluripotent stem cells. Nature Medicine
Choi SH, Kim YH, Hebisch M, et al. (2014) A three-dimensional human neural cell culture model of Alzheimer's disease. Nature. 515: 274-8
Chudnovsky Y, Kim D, Zheng S, et al. (2014) ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state. Cell Reports. 6: 313-24
Chung CY, Khurana V, Auluck PK, et al. (2013) Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7
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