Katrin F. Chua, Ph.D.

Affiliations: 
2001 Harvard University, Cambridge, MA, United States 
Area:
mRNA nuclear export, splicing
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"Katrin Chua"
Mean distance: 16.86 (cluster 11)
 
SNBCP

Parents

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Robin Reed grad student 2001 Harvard
 (Remodeling the spliceosome for exon ligation.)
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Publications

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Zheng W, Tasselli L, Li TM, et al. (2021) Mammalian SIRT6 Represses Invasive Cancer Cell Phenotypes through ATP Citrate Lyase (ACLY)-Dependent Histone Acetylation. Genes. 12
Chua KF. (2020) Chromatin Regulation and Genome Maintenance by Mammalian SIRT6 and SIRT7 The Faseb Journal. 34: 1-1
Chua K. (2020) Sirtuins: New Roles for Sirtuins in Aging and Disease Innovation in Aging. 4: 741-741
You W, Zheng W, Weiss S, et al. (2019) Structural basis for the activation and inhibition of Sirtuin 6 by quercetin and its derivatives. Scientific Reports. 9: 19176
Wang WW, Angulo-Ibanez M, Lyu J, et al. (2019) A Click Chemistry Approach Reveals the Chromatin-Dependent Histone H3K36 Deacylase Nature of SIRT7. Journal of the American Chemical Society
Paredes S, Angulo-Ibanez M, Tasselli L, et al. (2018) The epigenetic regulator SIRT7 guards against mammalian cellular senescence induced by ribosomal DNA instability. The Journal of Biological Chemistry
You W, Rotili D, Li TM, et al. (2016) Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules. Angewandte Chemie (International Ed. in English)
Tasselli L, Zheng W, Chua KF. (2016) SIRT6: Novel Mechanisms and Links to Aging and Disease. Trends in Endocrinology and Metabolism: Tem
Paredes S, Chua KF. (2016) SIRT7 clears the way for DNA repair. The Embo Journal
Tasselli L, Xi Y, Zheng W, et al. (2016) SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence. Nature Structural & Molecular Biology
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