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Yumi Ueki, Ph.D.

Affiliations: 
2009 University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
gp130/STAT3, neuroprotection
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John D. Ash grad student 2009 University of Oklahoma Health Sciences Center
 (Identification of an essential role of gp130 and STAT3 in endogenous neuroproteciton.)

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Publications

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Ueki Y, Shchepetkina V, Lefcort F. (2018) Retina-specific loss of causes mitochondrial dysfunction that leads to selective retinal ganglion cell degeneration in a mouse model of familial dysautonomia. Disease Models & Mechanisms
Lefcort F, Mergy M, Ohlen SB, et al. (2017) Animal and cellular models of familial dysautonomia. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society
Chaverra M, George L, Mergy M, et al. (2017) The Familial Dysautonomia disease gene, Ikbkap/Elp1, is required in the developing and adult central nervous system. Disease Models & Mechanisms
Ueki Y, Ramirez G, Salcedo E, et al. (2016) Loss of Ikbkap Causes Slow, Progressive Retinal Degeneration in a Mouse Model of Familial Dysautonomia. Eneuro. 3
Ueki Y, Wilken MS, Cox KE, et al. (2015) Transgenic expression of the proneural transcription factor Ascl1 in Müller glia stimulates retinal regeneration in young mice. Proceedings of the National Academy of Sciences of the United States of America. 112: 13717-22
Ueki Y, Wilken MS, Cox KE, et al. (2015) A transient wave of BMP signaling in the retina is necessary for Müller glial differentiation. Development (Cambridge, England). 142: 533-43
Pollak J, Wilken MS, Ueki Y, et al. (2013) ASCL1 reprograms mouse Muller glia into neurogenic retinal progenitors. Development (Cambridge, England). 140: 2619-31
Ueki Y, Reh TA. (2013) EGF stimulates Müller glial proliferation via a BMP-dependent mechanism. Glia. 61: 778-89
Ueki Y, Karl MO, Sudar S, et al. (2012) P53 is required for the developmental restriction in Müller glial proliferation in mouse retina. Glia. 60: 1579-89
Ueki Y, Reh TA. (2012) Activation of BMP-Smad1/5/8 signaling promotes survival of retinal ganglion cells after damage in vivo. Plos One. 7: e38690
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