Élie Besserer-Offroy, Ph.D.
Affiliations: | 2010-2018 | Department of Pharmacology - Physiology | Université de Sherbrooke, Sherbrooke, Québec, Canada |
| 2018-2021 | Department of Pharmacology and Therapeutics | McGill University, Montreal, QC, Canada | |
| 2021-2023 | Department of Molecular and Medical Pharmacology | University of California, Los Angeles, Los Angeles, CA | |
| 2023- | UFR Santé / Inserm UMR-S 1086 Anticipe | Université de caen |
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Parents
Sign in to add mentor| Philippe Sarret | grad student | 2010-2018 | Université de Sherbrooke |
| Terence E. Hebert | post-doc | 2018-2021 | McGill (Chemistry Tree) |
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Publications
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| Midavaine É, Brouillette RL, Théberge E, et al. (2024) Discovery of a CCR2-targeting pepducin therapy for chronic pain. Pharmacological Research. 107242 |
| Pétigny C, Dumont AA, Giguère H, et al. (2022) Monitoring TRPC7 Conformational Changes by BRET Following GPCR Activation. International Journal of Molecular Sciences. 23 |
| Tran K, Sainsily X, Côté J, et al. (2022) Size-Reduced Macrocyclic Analogues of [Pyr]-apelin-13 Showing Negative Gα Bias Still Produce Prolonged Cardiac Effects. Journal of Medicinal Chemistry. 65: 531-551 |
| Michaelian N, Sadybekov A, Besserer-Offroy É, et al. (2021) Structural insights on ligand recognition at the human leukotriene B4 receptor 1. Nature Communications. 12: 2971 |
| Vivancos M, Fanelli R, Besserer-Offroy É, et al. (2021) Metabolically Stable Neurotensin Analogs Exert Potent and Long-Acting Analgesia Without Hypothermia. Behavioural Brain Research. 113189 |
| Besserer-Offroy É, Brouillette RL, Longpré JM, et al. (2020) Assessing Gα-signaling with IP-One: Single Plate Transfection and Assay Protocol for Cell-Based High-Throughput Assay. Bio-Protocol. 10: e3715 |
| Sadybekov AA, Brouillette RL, Marin E, et al. (2020) Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR. Biomolecules. 10 |
| Besserer-Offroy É, Tétreault P, Brouillette RL, et al. (2020) Data set describing the biological activity of JMV2009, a novel silylated neurotensin(8-13) analog. Data in Brief. 31: 105884 |
| Tétreault P, Besserer-Offroy É, Brouillette RL, et al. (2020) Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog. European Journal of Pharmacology. 173174 |
| Brouillette RL, Besserer-Offroy É, Mona CE, et al. (2020) Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain. Pharmacological Research. 104750 |