Jeffrey R. Holt

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
sensory hair cells
Website:
https://sites.google.com/site/holtgeleoclab/people
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"Jeffrey Holt"
Mean distance: 14 (cluster 6)
 
SNBCP

Children

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Michaela Levin grad student UVA
Jessica R. Risner grad student 2002-2008 UVA
Eric A. Stauffer grad student 2003-2008 UVA
Geoffrey C. Horwitz grad student 2006-2012 UVA
Ye Hyun Kim grad student 2008-2014 University of Virginia, Harvard
Charles Askew grad student 2008-2015 University of Virginia, Harvard
Xiao Ping Liu post-doc Harvard
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Publications

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Zheng W, Holt JR. (2020) The Mechanosensory Transduction Machinery in Inner Ear Hair Cells. Annual Review of Biophysics
Wu J, Solanes P, Nist-Lund C, et al. (2020) Single and dual vector gene therapy with AAV9-PHP.B rescues hearing in Tmc1 mutant mice. Molecular Therapy : the Journal of the American Society of Gene Therapy
Yeh WH, Shubina-Oleinik O, Levy JM, et al. (2020) In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness. Science Translational Medicine. 12
Lee J, Nist-Lund C, Solanes P, et al. (2020) Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B. Hearing Research. 107882
Marcovich I, Holt JR. (2020) Evolution and function of Tmc genes in mammalian hearing Current Opinion in Physiology. 18: 11-19
Meng X, Murali S, Cheng Y, et al. (2019) Increasing the Expression Level of ChR2 Enhances the Optogenetic Excitability of Cochlear Neurons. Journal of Neurophysiology
Thuronyi BW, Koblan LW, Levy JM, et al. (2019) Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity. Nature Biotechnology
Thuronyi BW, Koblan LW, Levy JM, et al. (2019) Continuous evolution of base editors with expanded target compatibility and improved activity. Nature Biotechnology
György B, Nist-Lund C, Pan B, et al. (2019) Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss. Nature Medicine
Nist-Lund CA, Pan B, Patterson A, et al. (2019) Publisher Correction: Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders. Nature Communications. 10: 734
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