Geoffrey D. Girnun, Ph.D.

Affiliations: 
2000 University of Iowa, Iowa City, IA 
Area:
radiation oncology
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"Geoffrey Girnun"
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Parents

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Michael E. Robbins grad student 2000 University of Iowa
 (Induction of catalase by peroxisome proliferator-activated receptor gamma (PPAR gamma) ligands: Identification of a PPAR gamma response element in the rat catalase promoter.)
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Publications

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Bott AJ, Peng IC, Fan Y, et al. (2015) Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation. Cell Metabolism
Montal ED, Dewi R, Bhalla K, et al. (2015) PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth. Molecular Cell
Choe M, Brusgard JL, Chumsri S, et al. (2015) The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells. Journal of Cellular Biochemistry
Choe M, Brusgard JL, Chumsri S, et al. (2015) The RUNX2 Transcription Factor Negatively Regulates SIRT6 Expression to Alter Glucose Metabolism in Breast Cancer Cells Journal of Cellular Biochemistry. 116: v
Bhalla K, Liu WJ, Thompson K, et al. (2014) Cyclin D1 represses gluconeogenesis via inhibition of the transcriptional coactivator PGC1α. Diabetes. 63: 3266-78
Singh A, Happel C, Manna SK, et al. (2013) Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis. The Journal of Clinical Investigation. 123: 2921-34
Vazquez F, Lim JH, Chim H, et al. (2013) PGC1α expression defines a subset of human melanoma tumors with increased mitochondrial capacity and resistance to oxidative stress. Cancer Cell. 23: 287-301
Clerc P, Carey GB, Mehrabian Z, et al. (2012) Rapid detection of an ABT-737-sensitive primed for death state in cells using microplate-based respirometry. Plos One. 7: e42487
Bhalla K, Hwang BJ, Dewi RE, et al. (2012) Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis. Cancer Prevention Research (Philadelphia, Pa.). 5: 544-52
Girnun GD. (2012) The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancer. Seminars in Cell & Developmental Biology. 23: 381-8
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