W Scott Young, M.D., Ph.D.

Affiliations: 
Section on Neural Gene Expression NIMH, NIH, Bethesda, MD, Bethesda, MD, United States 
Area:
oxytocin, vasopressin, behavior
Website:
http://www.nimh.nih.gov/labs-at-nimh/research-areas/clinics-and-labs/lcmr/snge/index.shtml
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"W Scott Young"
Bio:

Dr. Young received his B.A., M.D., and Ph.D from The Johns Hopkins University. The latter degree, obtained under the guidance of Michael Kuhar, described the development of in vitro receptor autoradiography and the first applications of the technique to the localization of neurotranmsitter receptors in human and other animal brains. Dr. Young then completed an internship in internal medicine at the University of Maryland and a residency in neurology at the University of Virginia. He joined the NIMH in 1984 where he has studied the paraventricular and supraoptic nuclei in the hypothalamus. Dr. Young's laboratory is currently using and creating knock-out and transgenic mice to study the roles of vasopressin and oxytocin in the brain.

Mean distance: 13.85 (cluster 6)
 
SNBCP

Parents

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Saul Roseman research assistant 1971-1972 Johns Hopkins (Chemistry Tree)
Julius Axelrod research assistant 1975 NIMH
 (Summer student)
Michael J. Kuhar grad student 1977-1980 Johns Hopkins
Michael Brownstein post-doc 1984-1990 NIMH, NIH, Bethesda, MD
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Publications

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Cymerblit-Sabba A, Smith AS, Williams Avram SK, et al. (2020) Inducing Partner Preference in Mice by Chemogenetic Stimulation of CA2 Hippocampal Subfield. Frontiers in Molecular Neuroscience. 13: 61
Williams Avram SK, Lee HJ, Fastman J, et al. (2019) NMDA Receptor in Vasopressin 1b Neurons Is Not Required for Short-Term Social Memory, Object Memory or Aggression. Frontiers in Behavioral Neuroscience. 13: 218
Smith AS, Korgan AC, Young WS. (2019) Oxytocin delivered nasally or intraperitoneally reaches the brain and plasma of normal and oxytocin knockout mice. Pharmacological Research. 104324
Cilz NI, Cymerblit-Sabba A, Young WS. (2018) Oxytocin and Vasopressin in the Rodent Hippocampus. Genes, Brain, and Behavior. e12535
Mayer B, Németh K, Krepuska M, et al. (2017) Vasopressin stimulates the proliferation and differentiation of red blood cell precursors and improves recovery from anemia. Science Translational Medicine. 9
Patial S, Stumpo DJ, Young WS, et al. (2016) Effects of combined tristetraprolin/tumor necrosis factor receptor deficiency on the splenic transcriptome. Molecular and Cellular Biology
Smith AS, Williams Avram SK, Cymerblit-Sabba A, et al. (2016) Targeted activation of the hippocampal CA2 area strongly enhances social memory. Molecular Psychiatry
Pagani JH, Williams Avram SK, Cui Z, et al. (2015) Raphe serotonin neuron-specific oxytocin receptor knockout reduces aggression without affecting anxiety-like behavior in male mice only. Genes, Brain, and Behavior. 14: 167-76
Pagani JH, Zhao M, Cui Z, et al. (2015) Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2. Molecular Psychiatry. 20: 490-9
Young WS. (2013) Shedding heat on oxytocin. Endocrinology. 154: 3961-2
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