Ranganath Mamidi, Ph.D.

Affiliations: 
2013 Veterinary and Comparative Anatomy, Pharmacology and Physiology Washington State University, Pullman, WA, United States 
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Murali Chandra grad student 2013 WSU
 (Role of the N-terminal region of troponin T in cardiac muscle contractile activation.)
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Publications

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Mamidi R, Holmes JB, Doh CY, et al. (2021) cMyBPC phosphorylation modulates the effect of omecamtiv mecarbil on myocardial force generation. The Journal of General Physiology. 153
Li J, Mamidi R, Doh CY, et al. (2020) AAV9 gene transfer of cMyBPC N-terminal domains ameliorates cardiomyopathy in cMyBPC deficient mice. Jci Insight
Holmes JB, Doh CY, Mamidi R, et al. (2020) Strategies for targeting the cardiac sarcomere: avenues for novel drug discovery. Expert Opinion On Drug Discovery. 1-13
Doh CY, Li J, Mamidi R, et al. (2019) The HCM-causing Y235S cMyBPC mutation accelerates contractile function by altering C1 domain structure. Biochimica Et Biophysica Acta. Molecular Basis of Disease
Mamidi R, Li J, Doh CY, et al. (2018) Lost in translation: Interpreting cardiac muscle mechanics data in clinical practice. Archives of Biochemistry and Biophysics. 662: 213-218
Mamidi R, Li J, Doh CY, et al. (2018) Impact of the Myosin Modulator Mavacamten on Force Generation and Cross-Bridge Behavior in a Murine Model of Hypercontractility. Journal of the American Heart Association. 7: e009627
Li J, Gresham KS, Mamidi R, et al. (2018) Sarcomere-based genetic enhancement of systolic cardiac function in a murine model of dilated cardiomyopathy. International Journal of Cardiology
Mamidi R, Li J, Gresham KS, et al. (2017) Dose-Dependent Effects of the Myosin Activator Omecamtiv Mecarbil on Cross-Bridge Behavior and Force Generation in Failing Human Myocardium. Circulation. Heart Failure. 10
Mamidi R, Gresham KS, Li J, et al. (2017) Cardiac myosin binding protein-C Ser(302) phosphorylation regulates cardiac β-adrenergic reserve. Science Advances. 3: e1602445
Mamidi R, Gresham KS, Li J, et al. (2017) Myosin Activator Omecamtiv Mecarbil Differentially Impacts the Contractile Properties of Skinned Myocardium from Failing and Donor Human Hearts Biophysical Journal. 112: 556a
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