Sampath K. Gollapudi, Ph.D.
Affiliations: | 2011 | Mechanical Engineering | Washington State University, Pullman, WA, United States |
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Ma W, Del Rio CL, Qi L, et al. (2024) Myosin in autoinhibited state(s), stabilized by mavacamten, can be recruited in response to inotropic interventions. Proceedings of the National Academy of Sciences of the United States of America. 121: e2314914121 |
Gollapudi SK, Ma W, Chakravarthy S, et al. (2021) Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States. Journal of Molecular Biology. 433: 167295 |
Gollapudi SK, Sa N, Nag S. (2020) Decoupling the Interacting Head Motif and the Super Relaxed State of Myosin in Reconstituted Cardiac Bipolar Thick Filaments Biophysical Journal. 118: 423a |
Ma W, Nag S, Chakravarthy S, et al. (2020) Effects of Mavacamten and Blebbistatin on the Small-Angle X-ray Scattering Structure of Human β-cardiac Myosin Biophysical Journal. 118: 422a |
Reda SM, Gollapudi SK, Chandra M. (2019) Developmental increase in β-MHC enhances sarcomere length-dependent activation in the myocardium. The Journal of General Physiology |
Sa N, Tomasic I, Gollapudi S, et al. (2019) Abstract 340: Myosin Regulatory Light Chain: A Major Player in Defining the ‘OFF’ State of Cardiac Myosin Circulation Research. 125 |
Sa N, Tomasic I, Gollapudi S, et al. (2018) Abstract 572: Role Of Human Cardiac RLC In Modulating The Super-relaxed State Of Myosin: A Cardiomyopathy Perspective Circulation Research. 123 |
Gollapudi SK, Reda SM, Chandra M. (2017) Omecamtiv Mecarbil Abolishes Length-Mediated Increase in Guinea Pig Cardiac Myofiber Ca(2+) Sensitivity. Biophysical Journal. 113: 880-888 |
Reda SM, Gollapudi SK, Chandra M. (2016) L71F mutation in rat cardiac troponin T augments crossbridge recruitment and detachment dynamics against α-myosin heavy chain, but not against β-myosin heavy chain. Journal of Muscle Research and Cell Motility |
Mickelson AV, Gollapudi SK, Chandra M. (2016) Cardiomyopathy-related mutation (A30V) in mouse cardiac troponin T divergently alters the magnitude of stretch activation in α- and β-myosin heavy chain fibers. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00487.2016 |