Joseph Bryan, PhD, University of Pennsylvania

Cell Biology Pacific Northwest Diabetes Research Institute, Seattle, WA, United States 
Cell Biology
"Joseph Bryan"

Mean distance: 15.69 (cluster 28)
Cross-listing: Cell Biology Tree


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Robert A Edwards grad student 1991-1995 Baylor (Cell Biology Tree)
George Perry post-doc 1979-1982
Lynne M. Coluccio post-doc 1985-1986 Baylor (Cell Biology Tree)
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Makar TK, Gerzanich V, Nimmagadda VK, et al. (2015) Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis. Journal of Neuroinflammation. 12: 210
Ortiz D, Bryan J. (2015) Neonatal Diabetes and Congenital Hyperinsulinism Caused by Mutations in ABCC8/SUR1 are Associated with Altered and Opposite Affinities for ATP and ADP. Frontiers in Endocrinology. 6: 48
Ortiz D, Gossack L, Quast U, et al. (2013) Reinterpreting the action of ATP analogs on K(ATP) channels. The Journal of Biological Chemistry. 288: 18894-902
Ortiz D, Voyvodic P, Gossack L, et al. (2012) Two neonatal diabetes mutations on transmembrane helix 15 of SUR1 increase affinity for ATP and ADP at nucleotide binding domain 2. The Journal of Biological Chemistry. 287: 17985-95
Su Y, Lam TK, He W, et al. (2012) Hypothalamic leucine metabolism regulates liver glucose production. Diabetes. 61: 85-93
Winkler M, Kühner P, Russ U, et al. (2012) Role of the amino-terminal transmembrane domain of sulfonylurea receptor SUR2B for coupling to K(IR)6.2, ligand binding, and oligomerization. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 287-98
Kühner P, Prager R, Stephan D, et al. (2012) Importance of the Kir6.2 N-terminus for the interaction of glibenclamide and repaglinide with the pancreatic K(ATP) channel. Naunyn-Schmiedeberg's Archives of Pharmacology. 385: 299-311
Fukuda Y, Aguilar-Bryan L, Vaxillaire M, et al. (2011) Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8. The Journal of Biological Chemistry. 286: 8481-92
Simard JM, Woo SK, Norenberg MD, et al. (2010) Brief suppression of Abcc8 prevents autodestruction of spinal cord after trauma. Science Translational Medicine. 2: 28ra29
Slucca M, Harmon JS, Oseid EA, et al. (2010) ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation. Diabetes. 59: 128-34
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