Howard Holtzer, PhD

Affiliations: 
Cell and Developmental Biology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Cytoskeleton, atin networks
Website:
http://www.med.upenn.edu/apps/faculty/index.php/g20001862/p4244
Google:
"Howard Holtzer"
Bio:

Guggenheim Fellow 1958

Mean distance: 14.74 (cluster 28)
 
SNBCP

Parents

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Paul A. Weiss grad student 1952 Chicago
 (Reconstitution of the urodele spinal cord following unilateral ablation)

Children

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Parker B. Antin grad student Penn (Cell Biology Tree)
Joseph Bryan grad student Penn
Tom Schultheiss grad student Penn
Harold Weintraub grad student 1971 Penn
Richard Kevin Hunt grad student 1974 Penn
Mark T. Groudine grad student 1970-1976 Penn
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Publications

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Zhang ZQ, Bish LT, Holtzer H, et al. (2009) Sarcomeric-alpha-actinin defective in vinculin-binding causes Z-line expansion and nemaline-like body formation in cultured chick myotubes. Experimental Cell Research. 315: 748-59
Zhang ZQ, Bish LT, Holtzer H, et al. (2009) Corrigendum to "Sarcomeric-alpha-actinin defective in vinculin-binding causes Z-line expansion and nemaline-like body formation in cultured chick myotubes" [Experimental Cell Research 315 (2009) 748-759] (DOI:10.1016/j.yexcr.2008.12.019) Experimental Cell Research. 315: 2140
Ojima K, Lin ZX, Bang M, et al. (2000) Distinct families of Z-line targeting modules in the COOH-terminal region of nebulin. The Journal of Cell Biology. 150: 553-66
Lin Z, Hijikata T, Zhang Z, et al. (1998) Dispensability of the actin-binding site and spectrin repeats for targeting sarcomeric alpha-actinin into maturing Z bands in vivo: implications for in vitro binding studies. Developmental Biology. 199: 291-308
Hijikata T, Lin ZX, Holtzer S, et al. (1997) Unanticipated temporal and spatial effects of sarcomeric alpha-actinin peptides expressed in PtK2 cells. Cell Motility and the Cytoskeleton. 38: 54-74
Lin ZX, Zhang ZQ, Han YL, et al. (1994) [Expression of myogenic differentiation program in cultured normal postmitotic mononucleated myoblasts and the aberrant differentiation in rhabdomyosarcoma cells]. Shi Yan Sheng Wu Xue Bao. 27: 79-89
Lin Z, Lu MH, Schultheiss T, et al. (1994) Sequential appearance of muscle-specific proteins in myoblasts as a function of time after cell division: evidence for a conserved myoblast differentiation program in skeletal muscle. Cell Motility and the Cytoskeleton. 29: 1-19
Yu KR, Hijikata T, Lin ZX, et al. (1994) Truncated desmin in PtK2 cells induces desmin-vimentin-cytokeratin coprecipitation, involution of intermediate filament networks, and nuclear fragmentation: a model for many degenerative diseases. Proceedings of the National Academy of Sciences of the United States of America. 91: 2497-501
Lu MH, DiLullo C, Schultheiss T, et al. (1992) The vinculin/sarcomeric-alpha-actinin/alpha-actin nexus in cultured cardiac myocytes. The Journal of Cell Biology. 117: 1007-22
Schultheiss T, Choi J, Lin ZX, et al. (1992) A sarcomeric alpha-actinin truncated at the carboxyl end induces the breakdown of stress fibers in PtK2 cells and the formation of nemaline-like bodies and breakdown of myofibrils in myotubes. Proceedings of the National Academy of Sciences of the United States of America. 89: 9282-6
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