Douglas E. Feldman, Ph.D.

Affiliations: 
2004 Stanford University, Palo Alto, CA 
Area:
Biology and of Genetics
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"Douglas Feldman"
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Parents

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Judith Frydman grad student 2004 Stanford
 (Chaperonin -mediated folding of the von Hippel -Lindau tumor suppressor protein.)
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Publications

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Shukla V, Halabelian L, Balagere S, et al. (2019) HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells. Molecular Cell
Uthaya Kumar DB, Chen CL, Liu JC, et al. (2015) TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-initiating Stem-like Cells in Livers of Mice. Gastroenterology
Siddique HR, Feldman DE, Chen CL, et al. (2015) NUMB Phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by NANOG-dependent mechanism in liver cancer. Hepatology (Baltimore, Md.)
Machida K, Feldman DE, Tsukamoto H. (2015) TLR4-dependent tumor-initiating stem cell-like cells (TICs) in alcohol-associated hepatocellular carcinogenesis. Advances in Experimental Medicine and Biology. 815: 131-44
Chen CL, Tsukamoto H, Liu JC, et al. (2013) Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells. The Journal of Clinical Investigation. 123: 2832-49
Feldman DE, Chen C, Punj V, et al. (2013) The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex. Plos One. 8: e57312
Machida K, Chen CL, Liu JC, et al. (2012) Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus. Journal of Gastroenterology and Hepatology. 27: 19-22
Feldman DE, Chen C, Punj V, et al. (2012) Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 829-34
Machida K, Chen C, Kashiwabara C, et al. (2011) Abstract 2447: Novel TLR4-Nanog stemness pathway in liver cancer stem cells confers resistance to TGF-β-mediated tumor suppression through YAP1 and IGF2BP3-AKT-mTOR Cancer Research. 71: 2447-2447
Machida K, Liu J, Kashiwabara C, et al. (2010) Abstract 5357: TLR4-dependent Nanog+ cancer stem cells exhibit defective TGF-β signaling through IGF-Akt-Yap1 pathway Cancer Research. 70: 5357-5357
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