Leon E. Chen, Ph.D.
Affiliations: | 2002 | Stanford University, Palo Alto, CA |
Area:
chemical and systems biologyGoogle:
"Leon Chen"Mean distance: 21373.2
Parents
Sign in to add mentor| Daria Mochly-rosen | grad student | 2002 | Stanford | |
| (Opposing cardioprotective effects of delta and epsilonPKC: Therapeutic peptides for the treatment of ischemic heart disease.) | ||||
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Publications
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| Miyaji Y, Walter S, Chen L, et al. (2011) Distribution of KAI-9803, a novel δ-protein kinase C inhibitor, after intravenous administration to rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1946-53 |
| Liron T, Chen LE, Khaner H, et al. (2007) Rational design of a selective antagonist of epsilon protein kinase C derived from the selective allosteric agonist, pseudo-RACK peptide. Journal of Molecular and Cellular Cardiology. 42: 835-41 |
| Toomayan GA, Chen LE, Jiang HX, et al. (2003) C1-esterase inhibitor and a novel peptide inhibitor improve contractile function in reperfused skeletal muscle. Microsurgery. 23: 561-7 |
| Inagaki K, Chen L, Ikeno F, et al. (2003) Inhibition of delta-protein kinase C protects against reperfusion injury of the ischemic heart in vivo. Circulation. 108: 2304-7 |
| Murriel CL, Inagaki K, Chen L, et al. (2003) δPKC inhibition during ishchemia and reperfusion: targeting BAD and the cell death machinery Journal of Cardiac Failure. 9: S66 |
| Ikeno F, Inagaki K, Chen L, et al. (2003) Inhibition of delta protein kinase C protects vascular injury and microcirculation from reperfusion injury in myocardial infarction Journal of the American College of Cardiology. 41: 373 |
| Lee F, Inagaki K, Chen L, et al. (2002) A novel inhibitor of _protein kinase-C as a therapeutic for ischemic reperfusion injury in acute coronary syndromes Journal of the American College of Cardiology. 39: 445 |
| Chen L, Ingaki K, Ikeno F, et al. (2002) 22 A role for delta PKC in cardiac reperfusion injury in vivo Journal of Molecular and Cellular Cardiology. 34: A38 |
| Chen L, Wright LR, Chen CH, et al. (2001) Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7). Chemistry & Biology. 8: 1123-9 |
| Chen L, Hahn H, Wu G, et al. (2001) Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and εPKC Proceedings of the National Academy of Sciences of the United States of America. 98: 11114-11119 |