Lorna Farrelly
Affiliations: | 2015- | Pharmacology & Systems Therapeutics | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
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| Al-Kachak A, Fulton SL, Farrelly LA, et al. (2023) Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior. Biorxiv : the Preprint Server For Biology |
| Fulton SL, Wenderski W, Lepack AE, et al. (2022) Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome. Nature Communications. 13: 6384 |
| Farrelly LA, Zheng S, Schrode N, et al. (2022) Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia. Nature Communications. 13: 2195 |
| Zhao S, Chuh KN, Zhang B, et al. (2021) Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Lepack AE, Werner CT, Stewart AF, et al. (2020) Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science (New York, N.Y.). 368: 197-201 |
| Farrelly L, Zhang S, Flaherty E, et al. (2020) T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS Schizophrenia Bulletin. 46: S234-S234 |
| Farrelly LA, Maze I. (2019) An emerging perspective on 'histone code' mediated regulation of neural plasticity and disease. Current Opinion in Neurobiology. 59: 157-163 |
| Farrelly LA, Thompson RE, Zhao S, et al. (2019) Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature |
| Lepack AE, Bagot RC, Peña CJ, et al. (2016) Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior. Proceedings of the National Academy of Sciences of the United States of America |
| Farrelly LA, Dill BD, Molina H, et al. (2016) Current Proteomic Methods to Investigate the Dynamics of Histone Turnover in the Central Nervous System. Methods in Enzymology. 574: 331-54 |