Rocco G. Gogliotti, Ph.D.

Affiliations: 
2012 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Molecular Neuroscience, Motor Control, Neurobiology of Disease
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"Rocco Gogliotti"
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Parents

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Christine Didonato grad student 2012 Northwestern
 (Spinal Muscular Atrophy is a Cell Autonomous Disease of the Motor Neuron.)
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Publications

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Cikowski J, Holt C, Arthur B, et al. (2022) Optimized Administration of the M PAM VU0467154 Demonstrates Broad Efficacy, but Limited Effective Concentrations in Mice. Acs Chemical Neuroscience
Vermudez SAD, Gogliotti RG, Arthur B, et al. (2021) Profiling beneficial and potential adverse effects of MeCP2 overexpression in a hypomorphic Rett syndrome mouse model. Genes, Brain, and Behavior
Fisher NM, AlHashim A, Buch AB, et al. (2021) A GRM7 mutation associated with developmental delay reduces mGlu7 expression and produces neurological phenotypes. Jci Insight
Gogliotti R, Fisher N, Stansley B, et al. (2018) Total RNA-sequencing of Rett Syndrome Autopsy Samples Identifies the M4 Muscarinic Receptor as a Novel Therapeutic Target. The Journal of Pharmacology and Experimental Therapeutics
Fisher NM, Gogliotti RG, Vermudez SAD, et al. (2017) Genetic Reduction or Negative Modulation of mGlu7 Does Not Impact Anxiety and Fear Learning Phenotypes in a Mouse Model of MECP2 Duplication Syndrome. Acs Chemical Neuroscience
Gogliotti RG, Klar R, Rook JM, et al. (2016) mGlu5 Positive Allosteric Modulation Normalizes Synaptic Plasticity Defects and Motor Phenotypes in a Mouse Model of Rett Syndrome. Human Molecular Genetics
Gogliotti RG, Cardona H, Singh J, et al. (2013) The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models. Human Molecular Genetics. 22: 4084-101
Gogliotti RG, Quinlan KA, Barlow CB, et al. (2012) Motor neuron rescue in spinal muscular atrophy mice demonstrates that sensory-motor defects are a consequence, not a cause, of motor neuron dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3818-29
Gogliotti RG, Lutz C, Jorgensen M, et al. (2011) Characterization of a commonly used mouse model of SMA reveals increased seizure susceptibility and heightened fear response in FVB/N mice. Neurobiology of Disease. 43: 142-51
Hammond SM, Gogliotti RG, Rao V, et al. (2010) Mouse survival motor neuron alleles that mimic SMN2 splicing and are inducible rescue embryonic lethality early in development but not late. Plos One. 5: e15887
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