Dirk Schubert
Affiliations: | University of Nijmegen, Nijmegen, Gelderland, Netherlands |
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Children
Sign in to add trainee| Martijn M. Selten | research assistant | 2009-2010 | University of Nijmegen |
| Stéphanie Miceli | grad student | University of Nijmegen |
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Publications
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| Scheper M, Sørensen FNF, Ruffolo G, et al. (2024) Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex. Acta Neuropathologica. 147: 80 |
| Yuan X, Puvogel S, van Rhijn JR, et al. (2023) A human in vitro neuronal model for studying homeostatic plasticity at the network level. Stem Cell Reports. 18: 2222-2239 |
| Wang S, Rhijn JV, Akkouh I, et al. (2022) Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway. Cell Reports. 39: 110790 |
| van Rhijn JR, Shi Y, Bormann M, et al. (2021) Brunner syndrome associated MAOA mutations result in NMDAR hyperfunction and increased network activity in human dopaminergic neurons. Neurobiology of Disease. 163: 105587 |
| Mossink B, van Rhijn JR, Wang S, et al. (2021) Cadherin-13 is a critical regulator of GABAergic modulation in human stem-cell-derived neuronal networks. Molecular Psychiatry |
| Negwer M, Piera K, Hesen R, et al. (2020) EHMT1 regulates Parvalbumin-positive interneuron development and GABAergic input in sensory cortical areas. Brain Structure & Function |
| Kummeling J, Stremmelaar DE, Raun N, et al. (2020) Characterization of SETD1A haploinsufficiency in humans and Drosophila defines a novel neurodevelopmental syndrome. Molecular Psychiatry |
| Klein Gunnewiek TM, Van Hugte EJH, Frega M, et al. (2020) m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity. Cell Reports. 31: 107538 |
| Frega M, Selten M, Mossink B, et al. (2020) Distinct Pathogenic Genes Causing Intellectual Disability and Autism Exhibit a Common Neuronal Network Hyperactivity Phenotype. Cell Reports. 30: 173-186.e6 |
| Frega M, Linda K, Keller JM, et al. (2019) Neuronal network dysfunction in a model for Kleefstra syndrome mediated by enhanced NMDAR signaling. Nature Communications. 10: 4928 |