Manus Ward

Affiliations: 
Royal College of Surgeons of Ireland, Dublin, County Dublin, Ireland 
Area:
Neurotoxicity
Website:
http://www.rcsi.ie/researchdb/research_piprofile.jsp?uid=46
Google:
"Manus Ward"
Mean distance: 17.4 (cluster 11)
 
SNBCP
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Publications

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Weisová P, Anilkumar U, Ryan C, et al. (2012) 'Mild mitochondrial uncoupling' induced protection against neuronal excitotoxicity requires AMPK activity. Biochimica Et Biophysica Acta. 1817: 744-53
D'Orsi B, Bonner H, Tuffy LP, et al. (2012) Calpains are downstream effectors of bax-dependent excitotoxic apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1847-58
Tsuchiya T, Bonner HP, Engel T, et al. (2011) Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo. The European Journal of Neuroscience. 33: 401-8
Weisová P, Dávila D, Tuffy LP, et al. (2011) Role of 5'-adenosine monophosphate-activated protein kinase in cell survival and death responses in neurons. Antioxidants & Redox Signaling. 14: 1863-76
Tuffy LP, Concannon CG, D'Orsi B, et al. (2010) Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition. Molecular and Cellular Biology. 30: 5484-501
Zhdanov AV, Ward MW, Taylor CT, et al. (2010) Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange. Biochimica Et Biophysica Acta. 1797: 1627-37
Bonner HP, Concannon CG, Bonner C, et al. (2010) Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability. Journal of Neurochemistry. 114: 606-16
Ward MW, Concannon CG, Whyte J, et al. (2010) The amyloid precursor protein intracellular domain(AICD) disrupts actin dynamics and mitochondrial bioenergetics. Journal of Neurochemistry. 113: 275-84
Concannon CG, Tuffy LP, Weisová P, et al. (2010) AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. The Journal of Cell Biology. 189: 83-94
Weisová P, Concannon CG, Devocelle M, et al. (2009) Regulation of glucose transporter 3 surface expression by the AMP-activated protein kinase mediates tolerance to glutamate excitation in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2997-3008
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