Rory Curtis
Affiliations: | Elixir Pharmaceuticals, Cambridge, MA, United States |
Area:
GAP43, glia, ion channels, regeneration, neurotrophins, GAP-43Google:
"Rory Curtis"Bio:
Email: rorycurtis@comcast.net ............ History: PhD, Biochemistry, Imperial College, London, UK;
Post-doc, Regeneron Pharmaceuticals, NY;
Lecturer, Bristol University, Bristol, UK;
Senior Scientist, Millennium Pharmaceuticals, MA;
Senior Director, Elixir Pharmaceuticals, MA;
Mean distance: 14.95 (cluster 11) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentorMichael R. Hanley | research assistant | 1985-1987 | Imperial College London |
Graham P. Wilkin | grad student | 1985-1991 | Imperial College London |
Peter S. DiStefano | post-doc | 1991-1995 | Regeneron Pharmaceuticals |
Ronald M. Lindsay | post-doc | 1991-1995 | Regeneron Pharmaceuticals |
Children
Sign in to add traineeScott Eliasof | research scientist | 2000-2001 | Millennium Pharmaceuticals |
Tara M. D'Eon | research scientist | 2006-2007 | Elixir Pharmaceuticals |
Julie Huber | research scientist | 2002-2008 | Elixir Pharmaceuticals |
Collaborators
Sign in to add collaboratorWilliam A. Catterall | collaborator | Wahington University | |
David E. Clapham | collaborator | Harvard Medical School/HHMI | |
Susan M. Hall | collaborator | Guy's Hospital, London | |
Mats H. Holmqvist | collaborator | Millennium Pharmaceuticals | |
Krisjan Jessen | collaborator | UCL | |
Irwin Levitan | collaborator | Boston University, Brandeis University | |
Rhona Mirsky | collaborator | UCL | |
John V. Priestley | collaborator | Thomas's Hospital, London | |
Steven S. Scherer | collaborator | Penn | |
Immaculada Silos-Santiago | collaborator | Millennium Pharmaceuticals | |
Barbara A. Spruce | collaborator | Imperial College, London | |
Helen Stewart | collaborator | UCL | |
Carlos Ibanez | collaborator | 1993-1995 | Regeneron Pharmaceuticals |
David Wynick | collaborator | 1995-1997 | University of Bristol |
BETA: Related publications
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Publications
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Longo KA, Govek EK, Nolan A, et al. (2012) Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity (Journal of Pharmacology and Experimental Therapeutics (2011) 339, (115-124)) Journal of Pharmacology and Experimental Therapeutics. 340: 810 |
Longo KA, Govek EK, Nolan A, et al. (2011) Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity. The Journal of Pharmacology and Experimental Therapeutics. 339: 115-24 |
DiStefano PS, Curtis R, Geddes BJ. (2007) Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan. Current Alzheimer Research. 4: 153-7 |
Curtis R, O'Connor G, DiStefano PS. (2006) Aging networks in Caenorhabditis elegans: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways. Aging Cell. 5: 119-26 |
Solomon JM, Pasupuleti R, Xu L, et al. (2006) Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Molecular and Cellular Biology. 26: 28-38 |
Napper AD, Hixon J, McDonagh T, et al. (2005) Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. Journal of Medicinal Chemistry. 48: 8045-54 |
McDonagh T, Hixon J, DiStefano PS, et al. (2005) Microplate filtration assay for nicotinamide release from NAD using a boronic acid resin. Methods (San Diego, Calif.). 36: 346-50 |
Curtis R, Geesaman BJ, DiStefano PS. (2005) Ageing and metabolism: drug discovery opportunities. Nature Reviews. Drug Discovery. 4: 569-80 |
Kaeberlein M, McDonagh T, Heltweg B, et al. (2005) Substrate-specific activation of sirtuins by resveratrol. The Journal of Biological Chemistry. 280: 17038-45 |
Apfeld J, O'Connor G, McDonagh T, et al. (2004) The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes & Development. 18: 3004-9 |