John S. Rudge

Affiliations: 
Regeneron Pharmaceuticals, Bernards, NJ, United States 
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"John Rudge"
Mean distance: 16.09 (cluster 11)
 
SNBCP
Cross-listing: Chemistry Tree

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Publications

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Eichten A, Su J, Adler A, et al. (2016) Resistance to anti-VEGF therapy mediated by autocrine IL-6/STAT3 signaling and overcome by IL-6 blockade. Cancer Research
Zhang L, Castanaro C, Luan B, et al. (2014) ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer models. Molecular Cancer Therapeutics. 13: 1345-55
Fraser HM, Hastings JM, Allan D, et al. (2012) Inhibition of delta-like ligand 4 induces luteal hypervascularization followed by functional and structural luteolysis in the primate ovary. Endocrinology. 153: 1972-83
Hoff BA, Bhojani MS, Rudge J, et al. (2012) DCE and DW-MRI monitoring of vascular disruption following VEGF-Trap treatment of a rat glioma model. Nmr in Biomedicine. 25: 935-42
Torres R, Macdonald L, Croll SD, et al. (2009) Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. Annals of the Rheumatic Diseases. 68: 1602-8
Huang J, Bae JO, Tsai JP, et al. (2009) Angiopoietin-1/Tie-2 activation contributes to vascular survival and tumor growth during VEGF blockade. International Journal of Oncology. 34: 79-87
Long DA, Price KL, Ioffe E, et al. (2008) Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury. Kidney International. 74: 300-9
Kadenhe-Chiweshe A, Papa J, McCrudden KW, et al. (2008) Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation. Molecular Cancer Research : McR. 6: 1-9
Nicoletti JN, Shah SK, McCloskey DP, et al. (2008) Vascular endothelial growth factor is up-regulated after status epilepticus and protects against seizure-induced neuronal loss in hippocampus. Neuroscience. 151: 232-41
Rudge JS, Ioffe E, Cao J, et al. (2008) Clinical development of VEGF trap Angiogenesis: An Integrative Approach From Science to Medicine. 415-420
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