Patrick G. Foran

Affiliations: 
Imperial College, London, London, England, United Kingdom 
Area:
ion channels, toxins
Google:
"Patrick Foran"
Mean distance: 17.75 (cluster 16)
 
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Publications

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Osborne SL, Latham CF, Wen PJ, et al. (2007) The Janus faces of botulinum neurotoxin: sensational medicine and deadly biological weapon. Journal of Neuroscience Research. 85: 1149-58
Foran PG, Davletov B, Meunier FA. (2003) Getting muscles moving again after botulinum toxin: novel therapeutic challenges. Trends in Molecular Medicine. 9: 291-9
Foran PG, Mohammed N, Lisk GO, et al. (2003) Evaluation of the therapeutic usefulness of botulinum neurotoxin B, C1, E, and F compared with the long lasting type A. Basis for distinct durations of inhibition of exocytosis in central neurons. The Journal of Biological Chemistry. 278: 1363-71
Li Y, Foran P, Lawrence G, et al. (2001) Recombinant Forms of Tetanus Toxin Engineered for Examining and Exploiting Neuronal Trafficking Pathways Journal of Biological Chemistry. 276: 31394-31401
O'Sullivan GA, Mohammed N, Foran PG, et al. (1999) Rescue of exocytosis in botulinum toxin A-poisoned chromaffin cells by expression of cleavage-resistant SNAP-25. Identification of the minimal essential C-terminal residues. The Journal of Biological Chemistry. 274: 36897-904
Chen F, Foran P, Shone CC, et al. (1997) Botulinum neurotoxin B inhibits insulin-stimulated glucose uptake into 3T3-L1 adipocytes and cleaves cellubrevin unlike type A toxin which failed to proteolyze the SNAP-23 present. Biochemistry. 36: 5719-28
Lawrence GW, Foran P, Dolly JO. (1996) Distinct exocytotic responses of intact and permeabilised chromaffin cells after cleavage of the 25-kDa synaptosomal-associated protein (SNAP-25) or synaptobrevin by botulinum toxin A or B. European Journal of Biochemistry / Febs. 236: 877-86
Li Y, Foran P, Fairweather NF, et al. (1994) A single mutation in the recombinant light chain of tetanus toxin abolishes its proteolytic activity and removes the toxicity seen after reconstitution with native heavy chain. Biochemistry. 33: 7014-20
Dolly J, de Paiva A, Foran P, et al. (1994) Probing the process of transmitter release with botulinum and tetanus neurotoxins Seminars in Neuroscience. 6: 149-158
de Paiva A, Ashton AC, Foran P, et al. (1993) Botulinum A like type B and tetanus toxins fulfils criteria for being a zinc-dependent protease. Journal of Neurochemistry. 61: 2338-41
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