Sarita Lagalwar, Ph.D.

2000-2007 Department of Cell and Molecular Biology Northwestern University, Evanston, IL 
 2008-2012 Institute for Translational Neuroscience University of Minnesota, Twin Cities, Minneapolis, MN 
 2012- Neuroscience Skidmore College, Saratoga Springs, NY, United States 
Neuroscience Biology, Cell Biology
"Sarita Lagalwar"
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Lester I. Binder grad student 2007 Northwestern
 (Neurofibrillary tangles and granulovacuolar degeneration bodies: Examining protein aggregation and accumulation.)
Harry T. Orr post-doc 2008-2012 UMN
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Huang H, Toker N, Burr E, et al. (2021) Intercellular Propagation and Aggregate Seeding of Mutant Ataxin-1. Journal of Molecular Neuroscience : Mn
Pérez Ortiz JM, Mollema N, Toker N, et al. (2018) Reduction of protein kinase A-mediated phosphorylation of ATXN1-S776 in Purkinje cells delays onset of Ataxia in a SCA1 mouse model. Neurobiology of Disease
Kohiyama MF, Lagalwar S. (2015) Stabilization and Degradation Mechanisms of Cytoplasmic Ataxin-1. Journal of Experimental Neuroscience. 9: 123-9
Lagalwar S, Orr HT. (2013) Regulation of ataxin-1 phosphorylation and its impact on biology. Methods in Molecular Biology (Clifton, N.J.). 1010: 201-9
Park J, Al-Ramahi I, Tan Q, et al. (2013) RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1. Nature. 498: 325-31
Oh KJ, Perez SE, Lagalwar S, et al. (2010) Staging of Alzheimer's pathology in triple transgenic mice: a light and electron microscopic analysis. International Journal of Alzheimer's Disease. 2010
Jorgensen ND, Andresen JM, Lagalwar S, et al. (2009) Phosphorylation of ATXN1 at Ser776 in the cerebellum. Journal of Neurochemistry. 110: 675-86
Sahara N, Murayama M, Lee B, et al. (2008) Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3beta is required for tau aggregation. The European Journal of Neuroscience. 27: 2897-906
Lagalwar S, Berry RW, Binder LI. (2007) Relation of hippocampal phospho-SAPK/JNK granules in Alzheimer's disease and tauopathies to granulovacuolar degeneration bodies. Acta Neuropathologica. 113: 63-73
Lagalwar S, Guillozet-Bongaarts AL, Berry RW, et al. (2006) Formation of phospho-SAPK/JNK granules in the hippocampus is an early event in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 455-64
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