Nichole E. LaPointe, Ph.D.

Affiliations: 
2008 Neuroscience Institute Graduate Program Northwestern University, Evanston, IL 
Area:
Neuroscience Biology, Cell Biology, Molecular Biology
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"Nichole LaPointe"
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Lester I. Binder grad student 2008 Northwestern
 (The N-terminus of tau in filament formation and the regulation of axonal transport: A perspective on tau assembly and toxicity.)
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Publications

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Feinstein HE, Benbow SJ, LaPointe NE, et al. (2016) Oligomerization of the Microtubule Associated Protein Tau is Mediated by its N-Terminal Sequences: Implications for Normal and Pathological Tau Action. Journal of Neurochemistry
Do TD, LaPointe NE, Nelson R, et al. (2015) Amyloid β-Protein C-terminal Fragments: Formation of Cylindrins and β-barrels. Journal of the American Chemical Society
Do TD, de Almeida NE, Lapointe NE, et al. (2015) Amino Acid Metaclusters: Implications of Growth Trends on Peptide Self-Assembly and Structure. Analytical Chemistry
de Almeida NE, Do TD, Tro M, et al. (2015) Opposing Effects of Cucurbit[7]uril and 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose on Amyloid β25-35 Assembly. Acs Chemical Neuroscience
Eschmann NA, Do TD, LaPointe NE, et al. (2015) Tau Aggregation Propensity Engrained in Its Solution State. The Journal of Physical Chemistry. B
Ganguly P, Do TD, Larini L, et al. (2015) Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3. The Journal of Physical Chemistry. B. 119: 4582-93
Levine ZA, Larini L, LaPointe NE, et al. (2015) Regulation and aggregation of intrinsically disordered peptides. Proceedings of the National Academy of Sciences of the United States of America. 112: 2758-63
Do TD, LaPointe NE, Sangwan S, et al. (2014) Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. The Journal of Physical Chemistry. B. 118: 7247-56
Yu D, LaPointe NE, Guzman E, et al. (2014) Tau proteins harboring neurodegeneration-linked mutations impair kinesin translocation in vitro. Journal of Alzheimer's Disease : Jad. 39: 301-14
Iyer A, Lapointe NE, Zielke K, et al. (2013) A novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function. Plos One. 8: e76409
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