Leonard K. Kaczmarek

Affiliations: 
Yale University, New Haven, CT 
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"Leonard Kaczmarek"
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Publications

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Khare S, Galeano K, Zhang Y, et al. (2018) C-terminal proline deletions in KCNC3 cause delayed channel inactivation and an adult-onset progressive SCA13 with spasticity. Cerebellum (London, England)
Chambers AR, Pilati N, Balaram P, et al. (2017) Pharmacological modulation of Kv3.1 mitigates auditory midbrain temporal processing deficits following auditory nerve damage. Scientific Reports. 7: 17496
Kaczmarek LK, Zhang Y. (2017) Kv3 Channels: Enablers of Rapid Firing, Neurotransmitter Release, and Neuronal Endurance. Physiological Reviews. 97: 1431-1468
Khare S, Nick JA, Zhang Y, et al. (2017) A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking. Plos One. 12: e0173565
Zhang Y, Ni W, Horwich AL, et al. (2017) An ALS-associated mutant SOD1 rapidly suppresses KCNT1 (Slack) Na+-activated K+ channels in Aplysia neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Onorati M, Li Z, Liu F, et al. (2016) Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia. Cell Reports
Fleming MR, Brown MR, Kronengold J, et al. (2016) Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex. Cell Reports
Brown MR, El-Hassar L, Zhang Y, et al. (2016) Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brainstem neurons. Journal of Neurophysiology. jn.00174.2016
Zhang Y, Zhang XF, Fleming MR, et al. (2016) Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell
Gribkoff VK, Kaczmarek LK. (2016) The Need for New Approaches in CNS Drug Discovery: Why Drugs Have Failed, and What Can Be Done to Improve Outcomes. Neuropharmacology
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