Katherine D. Cygnar

Johns Hopkins University, Baltimore, MD 
Olfactory Signal Transduction
"Katherine Cygnar"

Established a role for the Ca/CaM-dependent phosphodiesterase PDE1C in regulating olfactory adaptation but surprisingly not olfactory termination.

Mean distance: 16.79 (cluster 11)


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Haiqing Zhao grad student 2002-2009 Johns Hopkins
 (Regulation of olfactory signal transduction: Roles of phosphodiesterases and calcium /calmodulin desensitization of the cyclic nucleotide gated channel.)
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Cai Y, Nagel DJ, Zhou Q, et al. (2015) Role of cAMP-phosphodiesterase 1C signaling in regulating growth factor receptor stability, vascular smooth muscle cell growth, migration, and neointimal hyperplasia. Circulation Research. 116: 1120-32
Cygnar KD, Collins SE, Ferguson CH, et al. (2012) Phosphorylation of adenylyl cyclase III at serine1076 does not attenuate olfactory response in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 14557-62
Cygnar KD, Stephan AB, Zhao H. (2010) Analyzing responses of mouse olfactory sensory neurons using the air-phase electroolfactogram recording. Journal of Visualized Experiments : Jove
Stephan AB, Shum EY, Hirsh S, et al. (2009) ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification. Proceedings of the National Academy of Sciences of the United States of America. 106: 11776-81
Cygnar KD, Zhao H. (2009) Phosphodiesterase 1C is dispensable for rapid response termination of olfactory sensory neurons. Nature Neuroscience. 12: 454-62
Song Y, Cygnar KD, Sagdullaev B, et al. (2008) Olfactory CNG channel desensitization by Ca2+/CaM via the B1b subunit affects response termination but not sensitivity to recurring stimulation. Neuron. 58: 374-86
Cygnar KD, Gao X, Pan D, et al. (2005) The phosphatase subunit tap42 functions independently of target of rapamycin to regulate cell division and survival in Drosophila. Genetics. 170: 733-40
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