Vivek K. Unni, M.D., Ph.D.
Affiliations: | Neurology, Jungers | Oregon Health and Science University, Portland, OR |
Area:
Parkinson's Disease, 2-photon imagingGoogle:
"Vivek Unni"Mean distance: 13.57 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Steven A. Siegelbaum | grad student | 1998-2003 | Columbia | |
| (The role of presynaptic ryanodine -sensitive calcium stores in long-term depression.) | ||||
| Bradley T. Hyman | post-doc | 2007- | Harvard | |
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Publications
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| Rose EP, Osterberg VR, Banga JS, et al. (2024) Alpha-synuclein regulates the repair of genomic DNA double-strand breaks in a DNA-PK -dependent manner. Biorxiv : the Preprint Server For Biology |
| Weston LJ, Bowman AM, Osterberg VR, et al. (2022) Aggregated Alpha-Synuclein Inclusions within the Nucleus Predict Impending Neuronal Cell Death in a Mouse Model of Parkinsonism. International Journal of Molecular Sciences. 23 |
| Dent SE, King DP, Osterberg VR, et al. (2021) Phosphorylation of the aggregate-forming protein alpha-synuclein on serine-129 inhibits its DNA-bending properties. The Journal of Biological Chemistry. 101552 |
| Weber Boutros S, Raber J, Unni VK. (2021) Effects of Alpha-Synuclein Targeted Antisense Oligonucleotides on Lewy Body-Like Pathology and Behavioral Disturbances Induced by Injections of Pre-Formed Fibrils in the Mouse Motor Cortex. Journal of Parkinson's Disease |
| Weston LJ, Cook ZT, Stackhouse TL, et al. (2021) In vivo aggregation of presynaptic alpha-synuclein is not influenced by its phosphorylation at serine-129. Neurobiology of Disease. 105291 |
| Weston LJ, Stackhouse TL, Spinelli KJ, et al. (2021) Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies. The Journal of Biological Chemistry. 100273 |
| Schaser AJ, Stackhouse TL, Weston LJ, et al. (2020) Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy. Acta Neuropathologica Communications. 8: 150 |
| Schaser AJ, Osterberg VR, Dent SE, et al. (2019) Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders. Scientific Reports. 9: 10919 |
| Brockway NL, Cook ZT, O'Gallagher M, et al. (2019) Multicolor lineage tracing using in vivo time-lapse imaging reveals coordinated death of clonally related cells in the developing vertebrate brain. Developmental Biology |
| Schaser A, López CS, Unni V. (2019) Utilizing Correlated Light and Electron Microscopy to Examine Alpha-Synuclein Pathology in a Mouse Model of Parkinson's Disease Microscopy and Microanalysis. 25: 1132-1133 |