Derek G. Southwell, Ph.D.

Affiliations: 
2009 Neuroscience University of California, San Francisco, San Francisco, CA 
Area:
Neuroscience Biology
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Arturo Alvarez-Buylla grad student 2009 UCSF
 (Inhibitory neuron transplantation: Insights into the developmental cell death and ocular dominance plasticity of the cerebral cortex.)
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Publications

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Harward SC, Southwell DG. (2020) Interneuron transplantation: a prospective surgical therapy for medically refractory epilepsy. Neurosurgical Focus. 48: E18
Southwell DG, Seifikar H, Malik R, et al. (2020) Interneuron transplantation rescues social behavior deficits without restoring wild-type physiology in a mouse model of autism with excessive synaptic inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Southwell D, Seifikar H, Malik R, et al. (2019) Interneuron Transplantation Creates New Network States and Rescues Social Behavior Deficits in a Mouse Model of Autism Neurosurgery. 66
Southwell DG, Birk HS, Han SJ, et al. (2017) Resection of gliomas deemed inoperable by neurosurgeons based on preoperative imaging studies. Journal of Neurosurgery. 1-9
Southwell DG, Hervey-Jumper SL, Perry DW, et al. (2015) Intraoperative mapping during repeat awake craniotomy reveals the functional plasticity of adult cortex. Journal of Neurosurgery. 1-10
Southwell DG, Nicholas CR, Basbaum AI, et al. (2014) Interneurons from embryonic development to cell-based therapy. Science (New York, N.Y.). 344: 1240622
Nicholas CR, Chen J, Tang Y, et al. (2013) Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development. Cell Stem Cell. 12: 573-86
Southwell DG, Paredes MF, Galvao RP, et al. (2012) Intrinsically determined cell death of developing cortical interneurons. Nature. 491: 109-13
Southwell DG, Froemke RC, Alvarez-Buylla A, et al. (2010) Cortical plasticity induced by inhibitory neuron transplantation. Science (New York, N.Y.). 327: 1145-8
Baraban SC, Southwell DG, Estrada RC, et al. (2009) Reduction of seizures by transplantation of cortical GABAergic interneuron precursors into Kv1.1 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 15472-7
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