Megan M. McNulty, Ph.D.

Affiliations: 
2005 University of Chicago, Chicago, IL 
Area:
Pharmacology, General Biophysics
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"Megan McNulty"
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Dorothy Hanck grad student 2005 Chicago
 (State-dependent block of sodium and T-type calcium channels by mibefradil.)
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Publications

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Hanck DA, Nikitina E, McNulty MM, et al. (2009) Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity. Circulation Research. 105: 492-9
McNulty MM, Edgerton GB, Shah RD, et al. (2007) Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels. The Journal of Physiology. 581: 741-55
McNulty MM, Kyle JW, Lipkind GM, et al. (2006) An inner pore residue (Asn406) in the Nav1.5 channel controls slow inactivation and enhances mibefradil block to T-type Ca2+ channel levels. Molecular Pharmacology. 70: 1514-23
Freeze BS, McNulty MM, Hanck DA. (2006) State-dependent verapamil block of the cloned human Ca(v)3.1 T-type Ca(2+) channel. Molecular Pharmacology. 70: 718-26
Emerick MC, Stein R, Kunze R, et al. (2006) Profiling the array of Ca(v)3.1 variants from the human T-type calcium channel gene CACNA1G: alternative structures, developmental expression, and biophysical variations. Proteins. 64: 320-42
Lam AD, Chikina MD, McNulty MM, et al. (2005) Role of Domain IV/S4 outermost arginines in gating of T-type calcium channels. PflüGers Archiv : European Journal of Physiology. 451: 349-61
McNulty MM, Hanck DA. (2004) State-dependent mibefradil block of Na+ channels. Molecular Pharmacology. 66: 1652-61
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