Dani Brunner
Affiliations: | PsychoGenics Inc, Tarrytown, NY, United States |
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Alexandrov V, Brunner D, Menalled LB, et al. (2016) Large-scale phenome analysis defines a behavioral signature for Huntington's disease genotype in mice. Nature Biotechnology |
Onajole OK, Vallerini GP, Eaton JB, et al. (2016) Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III. Acs Chemical Neuroscience |
Wheeler VC, Kovalenko M, Giordano J, et al. (2016) B1 HTT CAG knock-in mice with pure and interrupted repeat tracts provide insight into the role of somatic expansion in HD pathogenesis Journal of Neurology, Neurosurgery & Psychiatry. 87: A9.2-A9 |
Yu LF, Brek Eaton J, Zhang HK, et al. (2014) The potent and selective α4β2*/α6*-nicotinic acetylcholine receptor partial agonist 2-[5-[5-((S)Azetidin-2-ylmethoxy)-3-pyridinyl]-3-isoxazolyl]ethanol demonstrates antidepressive-like behavior in animal models and a favorable ADME-tox profile. Pharmacology Research & Perspectives. 2: e00026 |
Milekic MH, Xin Y, O'Donnell A, et al. (2014) Age-related sperm DNA methylation changes are transmitted to offspring and associated with abnormal behavior and dysregulated gene expression. Molecular Psychiatry |
Farrar AM, Murphy CA, Paterson NE, et al. (2014) Cognitive deficits in transgenic and knock-in HTT mice parallel those in Huntington's disease. Journal of Huntington's Disease. 3: 145-58 |
Menalled LB, Kudwa AE, Oakeshott S, et al. (2014) Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease. Plos One. 9: e99520 |
Oakeshott S, Farrar A, Port R, et al. (2013) Deficits in a Simple Visual Go/No-go Discrimination Task in Two Mouse Models of Huntington's Disease. Plos Currents. 5 |
Kudwa AE, Menalled LB, Oakeshott S, et al. (2013) Increased Body Weight of the BAC HD Transgenic Mouse Model of Huntington's Disease Accounts for Some but Not All of the Observed HD-like Motor Deficits. Plos Currents. 5 |
Balci F, Oakeshott S, Shamy JL, et al. (2013) High-Throughput Automated Phenotyping of Two Genetic Mouse Models of Huntington's Disease. Plos Currents. 5 |