Dora Kovacs, PhD

Affiliations: 
Neurology Massachusetts General Hospital and Harvard University, Boston, MA, United States 
Area:
molecular events underlying neurodegeneration in aging, and particularly in Alzheimer’s disease
Website:
http://www.mghmind.org/Faculty/kovacs_dora.html
Google:
"Dora Kovacs"
Mean distance: 16.01 (cluster 28)
 
SNBCP
Cross-listing: Neuropathology Tree - Alzheimer's Tree

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Publications

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Lotlikar MS, Tarantino MB, Jorfi M, et al. (2022) Microfluidic separation of axonal and somal compartments of neural progenitor cells differentiated in a 3D matrix. Star Protocols. 3: 101028
Bhattacharyya R, Black SE, Lotlikar MS, et al. (2021) Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes. Cell Reports. 35: 109134
Bhattacharyya R, Fenn RH, Barren C, et al. (2016) Palmitoylated APP Forms Dimers, Cleaved by BACE1. Plos One. 11: e0166400
Kuzuya A, Zoltowska KM, Post KL, et al. (2016) Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. Bmc Biology. 14: 25
Gautam V, D'Avanzo C, Berezovska O, et al. (2015) Synaptotagmins interact with APP and promote Aβ generation. Molecular Neurodegeneration. 10: 31
D'Avanzo C, Sliwinski C, Wagner SL, et al. (2015) γ-Secretase modulators reduce endogenous amyloid β42 levels in human neural progenitor cells without altering neuronal differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Choi SH, Kim YH, Hebisch M, et al. (2014) A three-dimensional human neural cell culture model of Alzheimer's disease. Nature. 515: 274-8
Gautam V, D'Avanzo C, Hebisch M, et al. (2014) BACE1 activity regulates cell surface contactin-2 levels. Molecular Neurodegeneration. 9: 4
Kim DY, Wertz MH, Gautam V, et al. (2014) The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells. Neuro-Degenerative Diseases. 13: 64-8
Bhattacharyya R, Barren C, Kovacs DM. (2013) Palmitoylation of amyloid precursor protein regulates amyloidogenic processing in lipid rafts. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 11169-83
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