Pasha Grachev, Ph.D.
|2009-2013||Division of Women's Health||King's College London, London, UK|
|2013-2016||Physiology & Pharmacology||West Virgina University|
|2016-||Physiology & Pharmacology||Oregon Health and Science University, Portland, OR|
Area:Neuroendocrinology, neuroscience, endocrinology
Google:"Pasha Grachev neuroendocrinology"
I am a passionate young neuroendocrinologist with substantial experience in in vivo basic research on various aspects of hypothalamic regulation of reproductive function, as well as a desire to discover effective, non-invasive treatments targeting neural pathways implicated in metabolic syndrome and obesity. I routinely employ optogenetic, neuropharmacological and imaging techniques to address functional relationships between hypothalamic neurons, their afferent inputs, and feeding behavior. Outside of the lab, I am an aspiring musician, currently leading an original post-funk band. However, my favourite pastime is to embark upon adventures in the wilder parts of the world, which I traverse preferentially by motorcycle.
Mean distance: 23748
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|Fergani C, Mazzella L, Coolen LM, et al. (2016) Do Substance P and Neurokinin A Play Important Roles in the Control of LH Secretion in Ewes? Endocrinology. en20161565|
|Grachev P, Porter KL, Coolen LM, et al. (2016) Surge-like LH secretion induced by retrochiasmatic area NK3R activation is mediated primarily by ARC kisspeptin neurones in the ewe. Journal of Neuroendocrinology|
|Grachev P, Li XF, Goffin V, et al. (2015) Hypothalamic Prolactin Regulation of Luteinizing Hormone Secretion in the Female Rat. Endocrinology. 156: 2880-92|
|Grachev P, Li XF, Hu MH, et al. (2014) Neurokinin B signaling in the female rat: a novel link between stress and reproduction. Endocrinology. 155: 2589-601|
|Grachev P, Millar RP, O'Byrne KT. (2014) The role of neurokinin B signalling in reproductive neuroendocrinology. Neuroendocrinology. 99: 7-17|
|Grachev P, Li XF, O'Byrne K. (2013) Stress regulation of kisspeptin in the modulation of reproductive function. Advances in Experimental Medicine and Biology. 784: 431-54|
|Grachev P, Li XF, Lin YS, et al. (2012) GPR54-dependent stimulation of luteinizing hormone secretion by neurokinin B in prepubertal rats. Plos One. 7: e44344|
|Grachev P, Li XF, Kinsey-Jones JS, et al. (2012) Suppression of the GnRH pulse generator by neurokinin B involves a Îº-opioid receptor-dependent mechanism. Endocrinology. 153: 4894-904|
|Kinsey-Jones JS, Grachev P, Li XF, et al. (2012) The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat. Endocrinology. 153: 307-15|