Derek Bowie
Affiliations: | McGill University, Montreal, QC, Canada |
Area:
AMPA & Kainate receptors, NeurodevelopmentGoogle:
"Derek Bowie"Mean distance: 14.6 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentorTrevor G. Smart | grad student | 1987-1992 | School of Pharmacy, University of London |
Mark L. Mayer | post-doc | NIH | |
Paul Feltz | post-doc | 1992-1994 | University Louis Pasteur |
Children
Sign in to add traineeCollaborators
Sign in to add collaboratorFiona bedford | collaborator | 2007- | McGill |
Nicholas Moitessier | collaborator | 2007- | McGill (Chemistry Tree) |
Phil Barker | collaborator | 2008- | McGill |
Rikard Blunck | collaborator | 2008- | Université de Montréal |
Patrick Cossette | collaborator | 2008- | Université de Montréal |
Adriana Di Polo | collaborator | 2008- | Université de Montréal |
Philip Biggin | collaborator | 2011- | Oxford |
Jean-Marc Fritschy | collaborator | 2011- | Universität Zürich |
G David Lange | collaborator | 1997-2003 | NICHD |
John Marshall | collaborator | 2002-2003 | Brown |
Fiona bedford | collaborator | 2007-2011 | McGill |
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Publications
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Buschbom-Helmke S, Wang P, Alcaide A, et al. (2024) Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5). Journal of Medicinal Chemistry. 67: 14524-14542 |
Nakagawa T, Wang XT, Miguez-Cabello FJ, et al. (2024) The open gate of the AMPA receptor forms a Ca binding site critical in regulating ion transport. Nature Structural & Molecular Biology |
Larsen AH, Perozzo AM, Biggin PC, et al. (2024) Recovery from desensitization in GluA2 AMPA receptors is affected by a single mutation in the N-terminal domain interface. The Journal of Biological Chemistry. 300: 105717 |
Perozzo AM, Schwenk J, Kamalova A, et al. (2023) GSG1L-containing AMPA receptor complexes are defined by their spatiotemporal expression, native interactome and allosteric sites. Nature Communications. 14: 6799 |
Perozzo AM, Brown PMGE, Bowie D. (2023) Alternative splicing of the flip/flop cassette and TARP auxiliary subunits engage in a privileged relationship that fine-tunes AMPA receptor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
Saviuk N, Chong Y, Wang P, et al. (2022) Loss of 4E-BP converts cerebellar long-term depression to long-term potentiation. Cell Reports. 39: 110911 |
Brake N, Mancino AS, Yan Y, et al. (2022) Closed-state inactivation of cardiac, skeletal, and neuronal sodium channels is isoform specific. The Journal of General Physiology. 154 |
Mancino AS, Glass WG, Yan Y, et al. (2022) Spliced isoforms of the cardiac Nav1.5 channel modify channel activation by distinct structural mechanisms. The Journal of General Physiology. 154 |
Bowie D. (2022) The Many Faces of the AMPA-type Ionotropic Glutamate receptor. Neuropharmacology. 108975 |
Wyllie DJA, Bowie D. (2022) Ionotropic glutamate receptors: structure, function and dysfunction. The Journal of Physiology. 600: 175-179 |