Kenneth A. Jacobson

Affiliations: 
Molecular Recognition NIDDK, NIH, Bethesda, MD, United States 
Area:
GPCRs, adenosine, P2 receptors
Website:
https://www.niddk.nih.gov/about-niddk/staff-directory/biography/jacobson-kenneth
Google:
"Kenneth A Jacobson"
Mean distance: 18.3 (cluster 46)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Murray Goodman grad student 1981 UCSD (Chemistry Tree)
 (Monodisperse peptide conjugates of catecholamines : new congeners and carrier molecules)
Abraham Patchornik post-doc 1981-1983 Weizmann Institute (Chemistry Tree)

Children

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Eszter Kozma research assistant 2011-2012 Hungarian Academy of Sciences, Budapest (Chemistry Tree)
Elisa Uliassi research assistant 2014-2015 University of Bologna
Nandanan Erathodiyil post-doc 1998- NanoBio Lab, Singapore (Chemistry Tree)
Bilha Fischer post-doc 1992-1993 Bar-Ilan (Chemistry Tree)
Carola Gallo-Rodriguez post-doc 1992-1993 University of Buenos Aires, Faculty of Sciences (Chemistry Tree)
Jeongho Kim post-doc 1994-1995 Inha University (Chemistry Tree)
Emidio Camaioni post-doc 1997-1999 University of Perugia (Chemistry Tree)
Stefano Moro post-doc 1997-1999 University of Padua (Chemistry Tree)
Carsten Hoffmann post-doc 1998-2000 University of Wurzburg (Chemistry Tree)
Carsten Hoffmann post-doc 1998-2000 University of Wurzburg (Chemistry Tree)
Yong-Chul Kim post-doc 1998-2000 Gwangju Institute of Science and Technology (Chemistry Tree)
Kyeong Lee post-doc 2000-2001 NIDDK, National Institutes of Health (Chemistry Tree)
Bin Xu post-doc 2000-2002 shanghai university (Chemistry Tree)
Hak-Sung Kim post-doc 1999-2003 Wonkwang University (Chemistry Tree)
Wangzhong Chen post-doc 2002-2003 Guangzhou Medical University (Chemistry Tree)
Stefano Costanzi post-doc 2002-2004 NIDDK, NIH (Chemistry Tree)
Eun-Joo Roh post-doc 2003-2004 Korea Institute of Science and Technology (KIST) (Chemistry Tree)
Soo-Kyung Kim post-doc 2001-2006 Caltech (Chemistry Tree)
Hayamitsu Adachi post-doc 2005-2006 Institute of Microbial Chemistry, Tokyo (Chemistry Tree)
Pedro Besada post-doc 2002-2007 University of Vigo (Chemistry Tree)
Liaman Mamedova post-doc 2002-2007 Kansas State University (Chemistry Tree)
Yoonkyung Kim post-doc 2006-2007 Korea Research Institute of Bioscience and Biotechnology (KRIBB) (Chemistry Tree)
Hyojin Ko post-doc 2005-2008 Kwangju Inst. of Science and Technology (Chemistry Tree)
Sonia de Castro post-doc 2007-2009 La Agencia Estatal Consejo Superior de Investigaciones Científicas (Chemistry Tree)
Andrei A. Ivanov post-doc 2005-2010 Emory (Chemistry Tree)
Anna Junker post-doc 2014-2015 NIDDK, National Institutes of Health
Anna Junker post-doc 2014-2015 National Institutes of Health - NIDDK (Chemistry Tree)
Jinha Yu post-doc 2016-2018 KIST (Korea Institute of Science and Technology)
Ivar von Kügelgen research scientist 1998-2000 University of Bonn, Germany

Collaborators

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Ad P. IJzerman collaborator 1992- Leiden (Chemistry Tree)
Christa E. Müller collaborator 1992- University of Bonn, Germany
Bruce T. Liang collaborator 1996- University of Connecticut School of Medicine
Giampiero Spalluto collaborator 2001- University of Trieste, Italy (Chemistry Tree)
Lak Shin Jeong collaborator 2003- Seoul National University
John Auchampach collaborator 2008- Medical College of Wisconsin (Cell Biology Tree)
Daniela Salvemini collaborator 2010- St. Louis University (Anatomy Tree)
Raymond C. Stevens collaborator 2011- USC (Chemistry Tree)
Jens Carlsson collaborator 2012- Uppsala University, Sweden (Chemistry Tree)
Francesco Ciruela collaborator 2012- University of Barcelona, Spain (Chemistry Tree)
Gary L. Stiles collaborator 1987-1999 Duke Medical School
John W. Daly collaborator 1985-2003 NIDDK, National Institutes of Health
Bertil B. Fredholm collaborator 1985-2011 Karolinska
T. Kendall Harden collaborator 1993-2016 University of North Carolina at Chapel Hill School of Medicine (Chemistry Tree)
Mortimer M. Civan collaborator 2005-2016 University of Pennsylvania Medical School
Geoffrey Burnstock collaborator 1993-2020 Univerisity College London
BETA: Related publications

Publications

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Toti KS, Verma R, McGonnigle MJ, et al. (2022) Structure-Activity Relationship and Neuroprotective Activity of 1,5-Dihydro-2-naphtho[1,2-][1,4]diazepine-2,4(3)-diones as P2X4 Receptor Antagonists. Journal of Medicinal Chemistry
Jung YH, Shah Q, Lewicki SA, et al. (2022) Synthesis and pharmacological characterization of multiply substituted 2H-chromene derivatives as P2Y receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 75: 128981
Fisher CL, Fallot LB, Wan TC, et al. (2022) Characterization of Dual-Acting A Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gα and Gα Isoprotein Activation. Acs Pharmacology & Translational Science. 5: 625-641
Shiriaeva A, Park D, Kim G, et al. (2022) GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A Adenosine Receptor. Journal of Medicinal Chemistry
Puhl AC, Gao ZG, Jacobson KA, et al. (2022) Machine Learning for Discovery of New ADORA Modulators. Frontiers in Pharmacology. 13: 920643
Jacobson KA, Kim HS, Ravi G, et al. (2022) Engineering of A Adenosine and P2Y Nucleotide Receptors and Their Ligands. Drug Development Research. 58: 330-339
Kim YC, Karton Y, Ji XD, et al. (2022) Acyl-Hydrazide Derivatives of a Xanthine Carboxylic Congener (XCC) as Selective Antagonists at Human A Adenosine Receptors. Drug Development Research. 47: 178-188
Toti KS, Campbell RG, Lee H, et al. (2022) Fluorescent A and A adenosine receptor antagonists as flow cytometry probes. Purinergic Signalling
Merighi S, Borea PA, Varani K, et al. (2022) Pathophysiological Role and Medicinal Chemistry of A Adenosine Receptor Antagonists in Alzheimer's Disease. Molecules (Basel, Switzerland). 27
Suresh RR, Gao ZG, Salmaso V, et al. (2022) Selective A Adenosine Receptor Antagonist Radioligand for Human and Rodent Species. Acs Medicinal Chemistry Letters. 13: 623-631
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