Henry R. Bourne, M.D.

Affiliations: 
Pharmacology University of California, San Francisco, San Francisco, CA 
Website:
http://www.cmpharm.ucsf.edu/bourne/
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"Henry Bourne"
Bio:

(1940 - 2023)
https://www.ucsf.edu/news/2023/05/425236/remembering-henry-bourne-1940-2023
http://www.ucsf.edu/news/2011/12/11122/new-book-describes-ucsfs-metamorphosis-major-biomedical-center

Mean distance: 15.7 (cluster 11)
 
Cross-listing: Chemistry Tree

Children

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Orion D. Weiner grad student 2001 UCSF
Gary L. Johnson post-doc UCSF (Chemistry Tree)
David A. Sanders post-doc (Cell & Gene Therapy Tree)
Philip B. Wedegaertner post-doc Thomas Jefferson (Cell Biology Tree)
Bruce  R. Conklin post-doc 1990-1994 UCSF
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Publications

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Onsum MD, Wong K, Herzmark P, et al. (2006) Morphology matters in immune cell chemotaxis: membrane asymmetry affects amplification. Physical Biology. 3: 190-9
Wong K, Pertz O, Hahn K, et al. (2006) Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism. Proceedings of the National Academy of Sciences of the United States of America. 103: 3639-44
Weiner OD, Rentel MC, Ott A, et al. (2006) Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis. Plos Biology. 4: e38
Bourne HR. (2005) Rac and cell migration: CDM proteins integrate signals. Nature Cell Biology. 7: 777-8
Yu W, O'Brien LE, Wang F, et al. (2003) Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures. Molecular Biology of the Cell. 14: 748-63
Srinivasan S, Wang F, Glavas S, et al. (2003) Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis. The Journal of Cell Biology. 160: 375-85
Gilman AG, Simon MI, Bourne HR, et al. (2002) Overview of the Alliance for Cellular Signaling. Nature. 420: 703-6
Bourne HR, Weiner O. (2002) A chemical compass. Nature. 419: 21
Weiner OD, Neilsen PO, Prestwich GD, et al. (2002) A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity. Nature Cell Biology. 4: 509-13
Wang F, Herzmark P, Weiner OD, et al. (2002) Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils. Nature Cell Biology. 4: 513-8
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