William J. Martin

Affiliations: 
Theravance, Inc, South San Francisco, CA, United States 
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"William Martin"
Mean distance: 14.53 (cluster 6)
 
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Publications

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Sun MK, Passaro AP, Latchoumane CF, et al. (2019) Extracellular vesicles mediate neuroprotection and functional recovery after traumatic brain injury. Journal of Neurotrauma
Smith JA, Bourdet DL, Patil DL, et al. (2015) Preclinical to clinical translation of CNS transporter occupancy of TD-9855, a novel norepinephrine and serotonin reuptake inhibitor. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18
Hegde SS, Hughes AD, Chen Y, et al. (2014) Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties. The Journal of Pharmacology and Experimental Therapeutics. 351: 190-9
Shen F, Tsuruda PR, Smith JA, et al. (2013) Relative contributions of norepinephrine and serotonin transporters to antinociceptive synergy between monoamine reuptake inhibitors and morphine in the rat formalin model. Plos One. 8: e74891
Pulido-Rios MT, McNamara A, Obedencio GP, et al. (2013) In vivo pharmacological characterization of TD-4208, a novel lung-selective inhaled muscarinic antagonist with sustained bronchoprotective effect in experimental animal models. The Journal of Pharmacology and Experimental Therapeutics. 346: 241-50
Van Orden LJ, Van Dyke PM, Saito DR, et al. (2013) A novel class of 3-(phenoxy-phenyl-methyl)-pyrrolidines as potent and balanced norepinephrine and serotonin reuptake inhibitors: synthesis and structure-activity relationships. Bioorganic & Medicinal Chemistry Letters. 23: 1456-61
McNamara A, Steinfeld T, Pulido-Rios MT, et al. (2012) Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β(2)-adrenoceptor agonist (MABA). Pulmonary Pharmacology & Therapeutics. 25: 357-63
Hong Q, Bakshi RK, Palucki BL, et al. (2011) Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Bioorganic & Medicinal Chemistry Letters. 21: 2330-4
McNamara A, Pulido-Rios MT, Hegde SS, et al. (2011) Application of the classical Einthoven model of bronchoconstriction to the study of inhaled bronchodilators in rodents. Journal of Pharmacological and Toxicological Methods. 63: 89-95
Tyagarajan S, Chakravarty PK, Zhou B, et al. (2010) Discovery of a novel class of biphenyl pyrazole sodium channel blockers for treatment of neuropathic pain. Bioorganic & Medicinal Chemistry Letters. 20: 7479-82
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