Stephen L. Helfand

Affiliations: 
Molecular Biology, Cell Biology and Biochemistry Brown University, Providence, RI 
Area:
Aging
Website:
http://www.brown.edu/Divisions/Medical_School/andera/profile.php?id=1127248882
Google:
"Stephen Helfand"
Mean distance: 14.46 (cluster 11)
 
SNBCP
Cross-listing: Cell Biology Tree

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Publications

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Wood JG, Jones BC, Jiang N, et al. (2016) Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila. Proceedings of the National Academy of Sciences of the United States of America
Willmes DM, Helfand SL, Birkenfeld AL. (2016) The longevity transporter mIndy (Slc13a5) as a target for treating hepatic steatosis and insulin resistance. Aging
Pu M, Ni Z, Wang M, et al. (2015) Trimethylation of Lys36 on H3 restricts gene expression change during aging and impacts life span. Genes & Development. 29: 718-31
Gorbunova V, Boeke JD, Helfand SL, et al. (2014) Human Genomics. Sleeping dogs of the genome. Science (New York, N.Y.). 346: 1187-8
Whitaker R, Gil MP, Ding F, et al. (2014) Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster. Aging. 6: 355-68
Ding F, Gil MP, Franklin M, et al. (2014) Transcriptional response to dietary restriction in Drosophila melanogaster. Journal of Insect Physiology. 69: 101-6
Zhu CT, Chang C, Reenan RA, et al. (2014) Indy gene variation in natural populations confers fitness advantage and life span extension through transposon insertion. Aging. 6: 58-69
Wood JG, Helfand SL. (2013) Chromatin structure and transposable elements in organismal aging. Frontiers in Genetics. 4: 274
Jiang N, Du G, Tobias E, et al. (2013) Dietary and genetic effects on age-related loss of gene silencing reveal epigenetic plasticity of chromatin repression during aging. Aging. 5: 813-24
Savva YA, Jepson JE, Chang YJ, et al. (2013) RNA editing regulates transposon-mediated heterochromatic gene silencing. Nature Communications. 4: 2745
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