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Dejian Ren

Biology University of Pennsylvania, Philadelphia, PA, United States 
calcium signaling, ion channel
"Dejian Ren"
Mean distance: 15.54 (cluster 11)
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Stray-Pedersen A, Cobben JM, Prescott TE, et al. (2015) Biallelic Mutations in UNC80 Cause Persistent Hypotonia, Encephalopathy, Growth Retardation, and Severe Intellectual Disability. American Journal of Human Genetics
Guo J, Zeng W, Chen Q, et al. (2015) Structure of the voltage-gated two-pore channel TPC1 from Arabidopsis thaliana. Nature
Cang C, Aranda K, Seo YJ, et al. (2015) TMEM175 Is an Organelle K(+) Channel Regulating Lysosomal Function. Cell. 162: 1101-12
Flourakis M, Kula-Eversole E, Hutchison AL, et al. (2015) A Conserved Bicycle Model for Circadian Clock Control of Membrane Excitability. Cell. 162: 836-48
Xu H, Ren D. (2015) Lysosomal physiology. Annual Review of Physiology. 77: 57-80
Cang C, Aranda K, Ren D. (2014) A non-inactivating high-voltage-activated two-pore Na⁺ channel that supports ultra-long action potentials and membrane bistability. Nature Communications. 5: 5015
Cang C, Bekele B, Ren D. (2014) The voltage-gated sodium channel TPC1 confers endolysosomal excitability. Nature Chemical Biology. 10: 463-9
Cang C, Zhou Y, Navarro B, et al. (2013) mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state. Cell. 152: 778-90
Wang X, Zhang X, Dong XP, et al. (2012) TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes. Cell. 151: 372-83
Kim BJ, Chang IY, Choi S, et al. (2012) Involvement of Na(+)-leak channel in substance P-induced depolarization of pacemaking activity in interstitial cells of Cajal. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 29: 501-10
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