J. Christopher Gant

Affiliations: 
Pharmacology University of Kentucky, Lexington, KY 
Area:
neuroscience, learning & memory, AHPs, intracellular calcium
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"J. Gant"
Mean distance: 17.23 (cluster 19)
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Philip W. Landfield grad student
Lucien T. Thompson grad student 1998-2003 UT Dallas
 (Neuronal excitability, learning and aging in the rat hippocampus.)
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Publications

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Gant JC, Chen KC, Kadish I, et al. (2015) Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10878-87
Maimaiti S, Anderson KL, DeMoll C, et al. (2015) Intranasal Insulin Improves Age-Related Cognitive Deficits and Reverses Electrophysiological Correlates of Brain Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences
Gant JC, Blalock EM, Chen KC, et al. (2014) FK506-binding protein 1b/12.6: a key to aging-related hippocampal Ca2+ dysregulation? European Journal of Pharmacology. 739: 74-82
Furman JL, Sama DM, Gant JC, et al. (2012) Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 16129-40
Gant JC, Chen KC, Norris CM, et al. (2011) Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1693-703
Blalock EM, Phelps JT, Pancani T, et al. (2010) Effects of long-term pioglitazone treatment on peripheral and central markers of aging. Plos One. 5: e10405
Kadish I, Thibault O, Blalock EM, et al. (2009) Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1805-16
Gant JC, Thibault O, Blalock EM, et al. (2009) Decreased number of interneurons and increased seizures in neuropilin 2 deficient mice: implications for autism and epilepsy. Epilepsia. 50: 629-45
Gant JC, Thibault O. (2009) Action potential throughput in aged rat hippocampal neurons: regulation by selective forms of hyperpolarization. Neurobiology of Aging. 30: 2053-64
Thibault O, Gant JC, Landfield PW. (2007) Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store. Aging Cell. 6: 307-17
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