Junichi Komoto, Ph.D.
Affiliations: | 2002 | University of Kansas, Lawrence, KS, United States |
Area:
Molecular Biology, Biochemistry, General BiophysicsGoogle:
"Junichi Komoto"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Fusao Takusagawa | grad student | 2002 | University of Kansas | |
| (Structures and functions of key enzymes in methyl cycle: Guanidinoacetate methyltransferase and S-adenosylhomocysteine hydrolase.) | ||||
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Publications
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| Yamada T, Komoto J, Kasuya T, et al. (2008) A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies. Biochimica Et Biophysica Acta. 1780: 809-18 |
| Yamada T, Komoto J, Lou K, et al. (2007) Structure and function of eritadenine and its 3-deaza analogues: potent inhibitors of S-adenosylhomocysteine hydrolase and hypocholesterolemic agents. Biochemical Pharmacology. 73: 981-9 |
| Komoto J, Yamada T, Watanabe K, et al. (2006) Prostaglandin F2alpha formation from prostaglandin H2 by prostaglandin F synthase (PGFS): crystal structure of PGFS containing bimatoprost. Biochemistry. 45: 1987-96 |
| Yamada T, Komoto J, Saiki K, et al. (2006) Variation of loop sequence alters stability of cytolethal distending toxin (CDT): crystal structure of CDT from Actinobacillus actinomycetemcomitans. Protein Science : a Publication of the Protein Society. 15: 362-72 |
| Yamada T, Takata Y, Komoto J, et al. (2005) Catalytic mechanism of S-adenosylhomocysteine hydrolase: roles of His 54, Asp130, Glu155, Lys185, and Aspl89. The International Journal of Biochemistry & Cell Biology. 37: 2417-35 |
| Yamada T, Komoto J, Watanabe K, et al. (2005) Crystal structure and possible catalytic mechanism of microsomal prostaglandin E synthase type 2 (mPGES-2). Journal of Molecular Biology. 348: 1163-76 |
| Komoto J, Yamada T, Takata Y, et al. (2004) Catalytic mechanism of guanidinoacetate methyltransferase: crystal structures of guanidinoacetate methyltransferase ternary complexes. Biochemistry. 43: 14385-94 |
| Komoto J, Yamada T, Watanabe K, et al. (2004) Crystal structure of human prostaglandin F synthase (AKR1C3). Biochemistry. 43: 2188-98 |
| Komoto J, Yamada T, Takata Y, et al. (2004) Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of S-adenosylmethionine synthesis from ATP and Met. Biochemistry. 43: 1821-31 |
| Yamada T, Komoto J, Takata Y, et al. (2003) Crystal structure of serine dehydratase from rat liver. Biochemistry. 42: 12854-65 |