Paul R. Harrison

Affiliations: 
Beatson Institute for Cancer Research 
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"Paul Harrison"
Mean distance: 17.99 (cluster 32)
 
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Publications

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Thurlow JK, Peña Murillo CL, Hunter KD, et al. (2010) Spectral clustering of microarray data elucidates the roles of microenvironment remodeling and immune responses in survival of head and neck squamous cell carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 2881-8
Minty F, Thurlow JK, Harrison PR, et al. (2008) Telomere dysfunction in human keratinocytes elicits senescence and a novel transcription profile. Experimental Cell Research. 314: 2434-47
Hunter KD, Thurlow JK, Fleming J, et al. (2006) Divergent routes to oral cancer. Cancer Research. 66: 7405-13
Crighton D, Wilkinson S, O'Prey J, et al. (2006) DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell. 126: 121-34
O'Prey J, Brown J, Fleming J, et al. (2003) Effects of dietary flavonoids on major signal transduction pathways in human epithelial cells. Biochemical Pharmacology. 66: 2075-88
Muntoni A, Fleming J, Gordon KE, et al. (2003) Senescing oral dysplasias are not immortalized by ectopic expression of hTERT alone without other molecular changes, such as loss of INK4A and/or retinoic acid receptor-beta: but p53 mutations are not necessarily required. Oncogene. 22: 7804-8
Brown J, O'Prey J, Harrison PR. (2003) Enhanced sensitivity of human oral tumours to the flavonol, morin, during cancer progression: Involvement to the Akt and stress kinase pathways Carcinogenesis. 24: 171-177
McGregor F, Muntoni A, Fleming J, et al. (2002) Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine. Cancer Research. 62: 4757-66
Fleming J, Ghose A, Harrison PR. (2001) Molecular mechanisms of cancer prevention by selenium compounds. Nutrition and Cancer. 40: 42-9
Ghose A, Fleming J, El-Bayoumy K, et al. (2001) Enhanced sensitivity of human oral carcinomas to induction of apoptosis by selenium compounds: involvement of mitogen-activated protein kinase and Fas pathways. Cancer Research. 61: 7479-87
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