Jason P. Chua

Affiliations: 
University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Neurodegeneration
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"Jason Chua"
Mean distance: 18.17 (cluster 24)
 
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Publications

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Giorgetti E, Yu Z, Chua JP, et al. (2016) Rescue of Metabolic Alterations in AR113Q Skeletal Muscle by Peripheral Androgen Receptor Gene Silencing. Cell Reports. 17: 125-36
Chua JP, Reddy SL, Yu Z, et al. (2015) Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease. The Journal of Clinical Investigation. 125: 831-45
Renier KJ, Troxell-Smith SM, Johansen JA, et al. (2014) Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy. Endocrinology. 155: 2624-34
Chua JP, Reddy SL, Merry DE, et al. (2014) Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. Human Molecular Genetics. 23: 1376-86
Chua JP, Lieberman AP. (2013) Pathogenic mechanisms and therapeutic strategies in spinobulbar muscular atrophy. Cns & Neurological Disorders Drug Targets. 12: 1146-56
Wang AM, Miyata Y, Klinedinst S, et al. (2013) Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation. Nature Chemical Biology. 9: 112-8
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