Arun K. Shukla

Affiliations: 
Duke University, Durham, NC 
Area:
GPCRs
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"Arun Shukla"
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Publications

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Maharana J, Sano FK, Sarma P, et al. (2024) Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors. Science (New York, N.Y.). 383: 101-108
Yadav MK, Maharana J, Yadav R, et al. (2023) Molecular basis of anaphylatoxin binding, activation, and signaling bias at complement receptors. Cell
Sarma P, Carino CMC, Seetharama D, et al. (2023) Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system. Nature Communications. 14: 4808
Isaikina P, Petrovic I, Jakob RP, et al. (2023) A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes. Molecular Cell
Maharana J, Sarma P, Yadav MK, et al. (2023) Structural snapshots uncover a key phosphorylation motif in GPCRs driving β-arrestin activation. Molecular Cell
Grimes J, Koszegi Z, Lanoiselée Y, et al. (2023) Plasma membrane preassociation drives β-arrestin coupling to receptors and activation. Cell. 186: 2238-2255.e20
Sarma P, Shukla AK. (2022) Resonating with the signaling bias of CXCR7. Molecular Cell. 82: 3318-3320
Sarma P, Banerjee R, Shukla AK. (2022) Structural snapshot of a β-arrestin-biased receptor. Trends in Pharmacological Sciences
Baidya M, Chaturvedi M, Dwivedi-Agnihotri H, et al. (2022) Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody. Nature Communications. 13: 4634
Maharana J, Banerjee R, Yadav MK, et al. (2022) Emerging structural insights into GPCR-β-arrestin interaction and functional outcomes. Current Opinion in Structural Biology. 75: 102406
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