Maurizio De Pittà, PhD

Affiliations: 
2008-2013 School of Physics and Astronomy Tel Aviv University, Tel Aviv-Yafo, Tel Aviv District, Israel 
 2014-2017 BEAGLE Team INRIA Rhône-Alpes 
 2015-2016 Department of Neurobiology University of Chicago, Chicago, IL 
 2018-2021 Area of Mathematical Modeling with Multidisciplinary Applications (M3A) Basque Center for Applied Mathematics 
 2021- Department of Neuroscience University of the Basque Country, Leioa, Euskadi, Spain 
 2021- Department of Physiology University of Toronto, Toronto, ON, Canada 
 2021- Division of Clinical and Computational Neuroscience Krembil Research Institute, Toronto, Ontario 
Area:
computational neuroscience, neuron-glia interactions, neuron-glial networks, calcium signaling, Alzheimer's disease, computational glioscience, glial technologies
Website:
https://physiology.utoronto.ca/faculty/maurizio-de-pitta
Google:
"Maurizio De Pittà"
Bio:

My lab studies neuron-glial interactions (NGIs) and address the fundamental question of how brain circuits shape cognitive processing and vice versa. We use various tools at the crossroads of physics, mathematics, engineering, molecular biology, and bioinformatics to bridge the structure vs. function of NGIs across multiple scales of brain operation--from intracellular signaling to microcircuits and from large neuron-glial networks to behavior. We are particularly interested in harnessing NGIs for diagnosis and intervention in neurodegenerative disorders, mining multi-variate data sets from clinicians, geneticists and biologists, using computational models of NGIs, and engineering new technology to study NGIs in humans.

Mean distance: 15.7 (cluster 22)
 

Parents

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Eshel Ben-Jacob grad student 2006-2013 Tel Aviv University
 (PhD Computational Neuroscience)
Hugues Berry post-doc 2014-2017 INRIA Rhône-Alpes
Nicolas Brunel post-doc 2015-2017 Chicago

Collaborators

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Andrea Volterra collaborator 2012- University of Lausanne
Paolo Bonifazi collaborator 2018-
Gordon Erlebacher collaborator 2019- (Computer Science Tree)
BETA: Related publications

Publications

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De Pittà M, Brunel N. (2022) Multiple forms of working memory emerge from synapse-astrocyte interactions in a neuron-glia network model. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207912119
Kastanenka KV, Moreno-Bote R, De Pittà M, et al. (2019) A roadmap to integrate astrocytes into Systems Neuroscience. Glia
De Pittà M, Brunel N. (2016) Modulation of Synaptic Plasticity by Glutamatergic Gliotransmission: A Modeling Study. Neural Plasticity. 2016: 7607924
De Pittà M, Brunel N, Volterra A. (2015) Astrocytes: Orchestrating synaptic plasticity? Neuroscience
Wallach G, Lallouette J, Herzog N, et al. (2014) Glutamate mediated astrocytic filtering of neuronal activity. Plos Computational Biology. 10: e1003964
Lallouette J, De Pittà M, Ben-Jacob E, et al. (2014) Sparse short-distance connections enhance calcium wave propagation in a 3D model of astrocyte networks. Frontiers in Computational Neuroscience. 8: 45
De Pittà M, Volman V, Berry H, et al. (2012) Computational quest for understanding the role of astrocyte signaling in synaptic transmission and plasticity. Frontiers in Computational Neuroscience. 6: 98
Meshulam L, Galron R, Kanner S, et al. (2012) The role of the neuro-astro-vascular unit in the etiology of ataxia telangiectasia. Frontiers in Pharmacology. 3: 157
Fellin T, Ellenbogen JM, De Pittà M, et al. (2012) Astrocyte regulation of sleep circuits: experimental and modeling perspectives. Frontiers in Computational Neuroscience. 6: 65
De Pittà M, Volman V, Berry H, et al. (2011) A tale of two stories: astrocyte regulation of synaptic depression and facilitation. Plos Computational Biology. 7: e1002293
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