Maurizio De Pittà, PhD
Affiliations: | 2008-2013 | School of Physics and Astronomy | Tel Aviv University, Tel Aviv-Yafo, Tel Aviv District, Israel |
2014-2017 | BEAGLE Team | INRIA Rhône-Alpes | |
2015-2016 | Department of Neurobiology | University of Chicago, Chicago, IL | |
2018-2021 | Area of Mathematical Modeling with Multidisciplinary Applications (M3A) | Basque Center for Applied Mathematics | |
2021- | Department of Physiology | University of Toronto, Toronto, ON, Canada | |
2021- | Department of Neuroscience | University of the Basque Country, Leioa, Euskadi, Spain | |
2021- | Division of Clinical and Computational Neuroscience | Krembil Research Institute, Toronto, Ontario |
Area:
computational neuroscience, neuron-glia interactions, neuron-glial networks, calcium signaling, Alzheimer's disease, computational glioscience, glial technologiesWebsite:
https://physiology.utoronto.ca/faculty/maurizio-de-pittaGoogle:
"Maurizio De Pittà"Bio:
My lab studies neuron-glial interactions (NGIs) and address the fundamental question of how brain circuits shape cognitive processing and vice versa. We use various tools at the crossroads of physics, mathematics, engineering, molecular biology, and bioinformatics to bridge the structure vs. function of NGIs across multiple scales of brain operation--from intracellular signaling to microcircuits and from large neuron-glial networks to behavior. We are particularly interested in harnessing NGIs for diagnosis and intervention in neurodegenerative disorders, mining multi-variate data sets from clinicians, geneticists and biologists, using computational models of NGIs, and engineering new technology to study NGIs in humans.
Mean distance: 15.7 (cluster 22)
Parents
Sign in to add mentorEshel Ben-Jacob | grad student | 2006-2013 | Tel Aviv University | |
(PhD Computational Neuroscience) | ||||
Hugues Berry | post-doc | 2014-2017 | INRIA Rhône-Alpes | |
Nicolas Brunel | post-doc | 2015-2017 | Chicago |
Children
Sign in to add traineePamela Maldonaldo | grad student | 2022- | University of Valparaiso |
Zhenyang Sun | grad student | 2022- | University of Toronto |
Michelangelo Volpi | grad student | 2022- | Basque Center for Applied Mathematics |
Carlos Vivar Rios | grad student | 2018-2022 | University of Lausanne |
Giulio Bonifazi | grad student | 2019-2023 | Basque Center for Applied Mathematics |
Collaborators
Sign in to add collaboratorAndrea Volterra | collaborator | 2012- | University of Lausanne |
Paolo Bonifazi | collaborator | 2018- | |
Gordon Erlebacher | collaborator | 2019- | (Computer Science Tree) |
Publications
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Bonifazi G, Luchena C, Gaminde-Blasco A, et al. (2024) A nonlinear meccano for Alzheimer's emergence by amyloid β-mediated glutamatergic hyperactivity. Neurobiology of Disease. 194: 106473 |
Musotto R, Wanderlingh U, D'Ascola A, et al. (2024) Dynamics of astrocytes Ca signaling: a low-cost fluorescence customized system for 2D cultures. Frontiers in Cell and Developmental Biology. 12: 1320672 |
Chameh HM, Falby M, Movahed M, et al. (2023) Distinctive biophysical features of human cell-types: insights from studies of neurosurgically resected brain tissue. Frontiers in Synaptic Neuroscience. 15: 1250834 |
De Pittà M, Brunel N. (2022) Multiple forms of working memory emerge from synapse-astrocyte interactions in a neuron-glia network model. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207912119 |
Kastanenka KV, Moreno-Bote R, De Pittà M, et al. (2019) A roadmap to integrate astrocytes into Systems Neuroscience. Glia |
De Pittà M, Brunel N. (2016) Modulation of Synaptic Plasticity by Glutamatergic Gliotransmission: A Modeling Study. Neural Plasticity. 2016: 7607924 |
De Pittà M, Brunel N, Volterra A. (2015) Astrocytes: Orchestrating synaptic plasticity? Neuroscience |
Wallach G, Lallouette J, Herzog N, et al. (2014) Glutamate mediated astrocytic filtering of neuronal activity. Plos Computational Biology. 10: e1003964 |
Lallouette J, De Pittà M, Ben-Jacob E, et al. (2014) Sparse short-distance connections enhance calcium wave propagation in a 3D model of astrocyte networks. Frontiers in Computational Neuroscience. 8: 45 |
De Pittà M, Volman V, Berry H, et al. (2012) Computational quest for understanding the role of astrocyte signaling in synaptic transmission and plasticity. Frontiers in Computational Neuroscience. 6: 98 |